Evidence map›Paper›PMID 32185436›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2020

Long-term bone mineral density changes after surgical cure of patients with tumor-induced osteomalacia.

L Colangelo, J Pepe, L Nieddu, C Sonato, A Scillitani, D Diacinti, M Angelozzi, C Cipriani, S Minisola

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Treatment Advances in Tumor-Induced Osteomalacia.Calcified tissue international · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L ColangeloDepartment of Internal Medicine and Medical Disciplines, Sapienza University of Rome, Rome, Italy. luciano.colangelo@uniroma1.it.ORCID https://orcid.org/0000-0002-5835-9310
J PepeDepartment of Internal Medicine and Medical Disciplines, Sapienza University of Rome, Rome, Italy.
L NiedduFaculty of Economics, UNINT University, Via Cristoforo Colombo 200, 00147, Rome, Italy.
C SonatoDepartment of Internal Medicine and Medical Disciplines, Sapienza University of Rome, Rome, Italy.
A ScillitaniEndocrinology Unit, "Casa Sollievo della Sofferenza", IRCCS, San Giovanni Rotondo, Foggia, Italy.
D DiacintiDepartment of Radiology, Sapienza University of Rome, Rome, Italy.
M AngelozziDepartment of Internal Medicine and Medical Disciplines, Sapienza University of Rome, Rome, Italy.
C CiprianiDepartment of Internal Medicine and Medical Disciplines, Sapienza University of Rome, Rome, Italy.
S MinisolaDepartment of Internal Medicine and Medical Disciplines, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper reports our personal experience filling the gap regarding changes of bone mineral density after surgical treatment in patient suffering from tumor-induced osteomalacia.

introductionNo systematic data are available regarding long-term bone mineral density (BMD) changes after surgical cure of patients with tumor-induced osteomalacia.

methodsFrom October 2001 through April 2018, we studied 10 consecutive patients (mean age ± SD, 45.5 ± 13.8 years; 5 males and 5 females) with tumor-induced osteomalacia. We evaluated BMD when initially presented at our Center and after surgical removal of the tumor.

resultsBasal BMD and corresponding Z-score values (mean values ± SD) measured by DXA were as follows: L

conclusionThis is the first case series documenting an impressive increase of BMD at both lumbar and femoral sites, together with an improvement of trabecular microarchitecture as documented by TBS. This is the consequence of huge mineralization of the large amount of osteoid tissue after resolution of the disease.

Indexed as

Bone DensityOsteomalaciaParaneoplastic SyndromesAbsorptiometry, PhotonAdultCancellous BoneFemaleFemur NeckHumansLumbar VertebraeMaleMiddle AgedFibroblast growth factor 23TmP/GFRTumor-induced osteomalaciaVitamin D

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.