ArticleSocial psychiatry and psychiatric epidemiology2020
New antidepressant utilization pre- and post-bereavement: a population-based study of partners and adult children.
Article in Social psychiatry and psychiatric epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Ayahuasca-assisted meaning reconstruction therapy as an early resource for bereavement: a non-randomized clinical trial.Scientific reports · 2025Trial
- Dyadic death-preparedness concordance states and bereaved caregivers' health-related quality of life and psychological outcomes: a longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Psychotropic medication trajectories around parental bereavement and their association with suicide mortality among adolescents and young adults, a Swedish nationwide cohort study.Social psychiatry and psychiatric epidemiology · 2026Article
- Caregiving at end-of-life: How do family structure and dementia status impact antidepressant and anxiolytic prescriptions among families?Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Parental death and initiation of antidepressant treatment in surviving children and youth: a national register-based matched cohort study.EClinicalMedicine · 2023Article
- Modifiable factors of depressive-symptom trajectories from caregiving through bereavement.BMC palliative care · 2022Article
- Associations between beta-blocker use and psychological distress in bereaved adults with cardiovascular conditions.Stress and health : journal of the International Society for the Investigation of Stress · 2022Article
- Serious Mental Illness Exacerbation Post-Bereavement: A Population-Based Study of Partners and Adult Children.Clinical epidemiology · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
purposeBereavement is associated with increased morbidity and mortality, but few studies have examined the specific timing of depression onset. This study examines the risk of developing new-onset depression in adult children and partners by month, 1 year before and after death.
methodsUsing population-based registers in Denmark, we assembled a cohort of 236,000 individuals who died a natural death (2010-2016). Partners and adult children of the deceased were identified and demographic and prescription data were collected. GEE logistic regression was used to model whether the bereaved received a new antidepressant prescription around the death of their loved one across 24 time intervals (12 months before and after death).
resultsMale and female partners had an increase in receipt of new antidepressant prescriptions in the 11 months after the death of their partner, with a peak increase 2 or 3 months after death. Partners also increased new antidepressant prescription use 2 months before death. Characteristics of the decedents including cause of death were not associated with new antidepressant prescription in the surviving partner. Adult children did not have increased odds of being prescribed new antidepressants at any time.
conclusionBoth male and female partners have increase in new antidepressant utilization before and after the death of their partner. Our work points to the importance of supporting partners not only after the death of their partner, but also in the period before death when families may be actively engaged in caregiving for the seriously ill.
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