Evidence map›Paper›PMID 32185237›Full record

ArticleJournal of immunology research2020

The Response of Tissue Mast Cells to TLR3 Ligand Poly(I:C) Treatment.

Piotr Witczak, Ewa Brzezińska-Błaszczyk, Justyna Agier

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  6. The pLysRS-ApInternational journal of molecular sciences · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Piotr WitczakDepartment of Experimental Immunology, Faculty of Health Sciences, Medical University of Lodz, Lodz, Poland.
Ewa Brzezińska-BłaszczykDepartment of Experimental Immunology, Faculty of Health Sciences, Medical University of Lodz, Lodz, Poland.ORCID https://orcid.org/0000-0002-1466-4321
Justyna AgierDepartment of Experimental Immunology, Faculty of Health Sciences, Medical University of Lodz, Lodz, Poland.ORCID https://orcid.org/0000-0002-6759-5737
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mast cells (MCs) are found mainly at the anatomical sites exposed to the external environment; thus, they are localized close to blood vessels, lymphatic vessels, and a multitude of immune cells. Moreover, those cells can recognize invading pathogens through a range of surface molecules known as pathogen recognition receptors (PRRs), mainly Toll-like receptors (TLRs). MCs are extensively engaged in the control and clearance of bacterial infections, but much less is known about their contribution to antiviral host response as well as pathomechanisms of virus-induced diseases. In the study, we employed

Indexed as

AnimalsCell DegranulationCells, CulturedCytokinesFemaleHypersensitivityMast CellsPoly I-CRatsRats, WistarReceptors, IgERNA, Double-StrandedRNA VirusesRNA Virus InfectionsToll-Like Receptor 3CytokinesFCER1A protein, ratPoly I-CReceptors, IgERNA, Double-StrandedTLR3 protein, ratToll-Like Receptor 3

Identifiers

PMID32185237
PMCPMC7060451
OpenAlexW3006716538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.