Evidence map›Paper›PMID 32185144›Full record

ArticleFrontiers in cellular and infection microbiology2020

5-Methylindole Potentiates Aminoglycoside Against Gram-Positive Bacteria Including

Fengqi Sun, Mengmeng Bian, Zhongyan Li, Boyan Lv, Yuanyuan Gao, Yan Wang, Xinmiao Fu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Bacterial persisters: molecular mechanisms and therapeutic development.Signal transduction and targeted therapy · 2024
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. The secret lives of single cells.Microbial biotechnology · 2022
    Article
  10. Article
  11. Article
  12. Copper KillsAntibiotics (Basel, Switzerland) · 2020
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fengqi SunProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Mengmeng BianProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Zhongyan LiProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Boyan LvProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Yuanyuan GaoProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Yan WangProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Xinmiao FuProvincial University Key Laboratory of Cellular Stress Response and Metabolic Regulation, College of Life Sciences, Fujian Normal University, Fuzhou, China.
Fujian Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance/tolerance has become a severe threat to human and animal health. To combat antibiotic-resistant/tolerant bacteria, it is of significance to improve the efficacy of traditional antibiotics. Here we show that indole potentiates tobramycin to kill stationary-phase

Indexed as

Adenosine TriphosphateAminoglycosidesAnimalsAnti-Bacterial AgentsDisease Models, AnimalDose-Response Relationship, DrugDrug Resistance, Multiple, BacterialDrug SynergismDrug Therapy, CombinationEnterococcus faecalisIndolesMaleMiceMice, Inbred ICRMicrobial Sensitivity TestsOsmotic Pressure5-methylindoleAdenosine TriphosphateAminoglycosidesAnti-Bacterial AgentsIndolesTobramycin5-Methylindoleaminoglycosideantibiotic resistanceantibiotic tolerancegram-positive bacteriaindolepersisterStaphylococcus aureus

Identifiers

PMID32185144
PMCPMC7058972
OpenAlexW3008083201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.