ArticleACS medicinal chemistry letters2020
Structure-Activity Relationship and Anticancer Profile of Second-Generation Anti-MRSA Synthetic Retinoids.
Article in ACS medicinal chemistry letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Thiophene-Engineered Lipid II Recognition Enables Potent Membranolytic Eradication of MRSA.Angewandte Chemie (International ed. in English) · 2026Article
- Preparation and Characterization of Zein/Salecan Nanocomposite Particles for Enhanced Stability and Bioactivity of Lipophilic Retinoids.Chemistry, an Asian journal · 2026Article
- Drug Repurposing: An Emerging Strategy inJournal of microbiology and biotechnology · 2025Review
- β-Cyclodextrin-optimized supramolecular nanovesicles enhance the droplet/foliage interface interactions and inhibition of succinate dehydrogenase (SDH) for efficient treatment of fungal diseases.Journal of nanobiotechnology · 2024Article
- Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection.Antimicrobial agents and chemotherapy · 2023Article
- Antimicrobial activity of a new class of synthetic retinoid antibiotics and comparator agents against ocular staphylococci.Frontiers in antibiotics · 2023Article
- Using membrane perturbing small molecules to target chronic persistent infections.RSC medicinal chemistry · 2021Review
- New Antimicrobials Based on the Adarotene Scaffold with Activity against Multi-Drug ResistantAntibiotics (Basel, Switzerland) · 2021Article
- Synthesis and biological evaluation of an antibacterial azaborine retinoid isostereTetrahedron letters · 2021Article
- Repurposing Clinically Approved Drugs for the Treatment ofACS omega · 2020Article
- Recent Advances Regarding the Therapeutic Potential of Adapalene.Pharmaceuticals (Basel, Switzerland) · 2020Review
- Addition of ethylamines to the phenols of bithionol and synthetic retinoids does not elicit activity in gram-negative bacteria.Bioorganic & medicinal chemistry letters · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
We previously reported the antibacterial activity of CD437, a known antitumor compound. It proved to be a potent antimicrobial agent effective against both growing and persister cells of methicillin-resistant
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.