ReviewFrontiers in pharmacology2020
A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases.
Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
142 citing papers in PubMed, 307 citations in OpenAlex.
- A phase II randomized, double-blind, placebo-controlled study of Nuvastatic (C50SEW505OESA), a standardized rosmarinic acid-rich polymolecular botanical extract formulation to reduce cancer-related fatigue in patients with solid tumors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- Protective effects of rosmarinic acid against carbaryl-exposed toxicity in honey bees (Apis mellifera): histopathological and molecular docking evidence.Veterinary research communications · 2026Article
- Dietary Rosmarinic Acid Improved the Growth, Immunity and Antioxidation ofAnimals : an open access journal from MDPI · 2026Article
- Inhibitory Efficacy of Medicinal Plant Extracts from the Family Acanthaceae Against Skin Pathogenic Bacteria, Antioxidant and Anti-Inflammatory Activities.Plants (Basel, Switzerland) · 2026Article
- Phytochemical Profiling, In Vitro Bioactivity, and Network Pharmacology ofMolecules (Basel, Switzerland) · 2026Article
- Phytochemical Profiling, Biological Evaluation, and Molecular Insights Into the Urease Inhibitory Potential of Fraxinus angustifolia Crude Extract and Fractions.Chemistry & biodiversity · 2026Article
- Article
- Protective role of rosmarinic acid against radiation-induced dermatitis: focus on oxidative stress and inflammation.BMC complementary medicine and therapies · 2026Article
- Lavandin cell extract enriched in rosmarinic acid attenuates inflammation via AMPK/Nrf2/HO-1 activation and IKK/IκB/NF-κB inhibition.BMC plant biology · 2026Article
- Organ-Specific Phytochemical Profiles, Wound-Healing and Hemostatic Activities ofMolecules (Basel, Switzerland) · 2026Article
- The influence of rosmarinic acid on male reproductive health: Biological mechanisms and clinical prospects.Biochemistry and biophysics reports · 2026Review
- Targeting Autoimmune Myocarditis with Lemon Balm Extract: In Vivo Molecular Approach.International journal of molecular sciences · 2026Article
- Multi-Kingdom Synergy ofLife (Basel, Switzerland) · 2026Review
- Comparison of Selected Pro-Health Biologically Active Chemical Compounds inMolecules (Basel, Switzerland) · 2026Article
- Eating and Mental Health Disorders.Nutrients · 2026Article
- Effect of short-duration microwave treatments on flower development and secondary metabolite production in Agastache rugosa.Scientific reports · 2026Article
- A natural nephroprotective adjuvant for cancer chemotherapy: Rosmarinic acid disrupts IL-17 A-Ferroptosis coupling in Ifosfamide-induced renal injury.Medical oncology (Northwood, London, England) · 2026Article
- Rosmarinic Acid Inhibits PRV Replication by Regulating Oxidative Stress Through the Nrf2 Signaling Pathway.Animals : an open access journal from MDPI · 2026Article
- Wound Healing Potential of the Salvianolic Acid H and Yunnaneic Acid B-The Rosmarinic Acid Derivatives: Anti-Inflammatory Action and Hemocompatibility In Vitro.Molecules (Basel, Switzerland) · 2026Article
- Enhancing secondary metabolite accumulation in medicinal plants to improve immunomodulatory activity.Frontiers in pharmacology · 2026Review
82 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory diseases are caused by abnormal immune responses and are characterized by an imbalance of inflammatory mediators and cells. In recent years, the anti-inflammatory activity of natural products has attracted wide attention. Rosmarinic acid (RosA) is a water-soluble phenolic compound that is an ester of caffeic acid and 3, 4-dihydroxyphenyl lactic acid. It is discovered in many plants, like those of the Boraginaceae and Lamiaceae families. RosA has a wide range of pharmacological effects, including anti-oxidative, anti-apoptotic, anti-tumorigenic, and anti-inflammatory effects. The anti-inflammatory effects of RosA have been revealed through
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.