Evidence map›Paper›PMID 32184692›Full record

ArticleJournal of blood medicine2020

Apixaban in a Morbid Obese Patient with Atrial Fibrillation: A Clinical Experience Using the Plasmatic Drug Evaluation.

Vincenzo Russo, Andrea Paccone, Anna Rago, Valeria Maddaloni, Dario Iafusco, Riccardo Proietti, Umberto Atripaldi, Antonio D'Onofrio, Paolo Golino, Gerardo Nigro

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of blood medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Obesity and cardiovascular disease: Risk assessment, physical activity, and management of complications.International journal of cardiology. Cardiovascular risk and prevention · 2024
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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Vincenzo RussoChair of Cardiology, University of Campania "Luigi Vanvitelli"- Monaldi Hospital, Naples, Italy.
Andrea PacconeChair of Cardiology, University of Bari "Aldo Moro", Bari, Italy.
Anna RagoChair of Cardiology, University of Campania "Luigi Vanvitelli"- Monaldi Hospital, Naples, Italy.
Valeria MaddaloniChemical Biochemistry Unit, Monaldi Hospital, Naples, Italy.
Dario IafuscoDepartment of Pediatrics, University of Campania "Luigi Vanvitelli", Naples, Italy.
Riccardo ProiettiChair of Cardiology, University of Padua, Padua, Italy.
Umberto AtripaldiChemical Biochemistry Unit, Monaldi Hospital, Naples, Italy.
Antonio D'OnofrioChair of Cardiology, University of Campania "Luigi Vanvitelli"- Monaldi Hospital, Naples, Italy.
Paolo GolinoChair of Cardiology, University of Campania "Luigi Vanvitelli"- Monaldi Hospital, Naples, Italy.
Gerardo NigroChair of Cardiology, University of Campania "Luigi Vanvitelli"- Monaldi Hospital, Naples, Italy.ORCID 0000-0003-1776-8449
University of Campania "Luigi Vanvitelli" · ITOspedale Monaldi · ITUniversity of Bari Aldo Moro · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 45-year-old man with atrial fibrillation and morbid obesity (weight 128 kg, height 168 cm, BMI 45.4) who was switched from Warfarin 5 mg once daily to Apixaban 5 mg twice daily because he did not achieve at least 60% of the time in therapeutic range. We performed serial determinations of apixaban plasma concentration (at 2, 6, 12, 24 hrs after intake) showing drug levels within reference range, even when the patient lose weight.

Indexed as

apixabanatrial fibrillationnon-vitamin k oral anticoagulantobesityplasma levelsweight loss

Identifiers

PMID32184692
PMCPMC7061727
OpenAlexW3010321861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.