ArticleClinical epidemiology2020
Patterns of Multimorbidity and Differences in Healthcare Utilization and Complexity Among Acutely Hospitalized Medical Patients (≥65 Years) - A Latent Class Approach.
Article in Clinical epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Patterns of multimorbidity, their outcomes and analytical methods for their determination: a systematic review.BMC public health · 2026Pooled it
- A systematic review and meta-analysis of disease clusters in multimorbidity.Nature communications · 2025Pooled it
- Variations in multimorbidity measurement in studies evaluating hospitalisation in older adults: a systematic review.BMC geriatrics · 2025Pooled it
- Association between multimorbidity and hospitalization in older adults: systematic review and meta-analysis.Age and ageing · 2022Pooled it
- Trial
- Healthcare utilization and chronic condition clusters in multimorbidity patients using weighted k-means: a register-based study in Denmark.Health information science and systems · 2026Article
- The Lifeworld of the Complex Care Hospital Doctor: A Complex Adaptive Phenomenological Study.Health care analysis : HCA : journal of health philosophy and policy · 2026Article
- Chronic disease comorbidity and its impact on healthcare utilization among older adults in China: a cross-sectional and longitudinal analysis.BMC geriatrics · 2026Article
- The association between health literacy and out-of-pocket health expenditure: exploring heterogeneity by chronic disease in Zhejiang, China.International journal for equity in health · 2026Article
- Unveiling the heterogeneity of T2DM: a narrative review of clustering algorithms in stratifying comorbidity and complication risk.Cardiovascular diabetology. Endocrinology reports · 2026Review
- Identifying 20 homogeneous clusters of acute patients discharged with nonspecific diagnoses through k-prototypes mixed data clustering.BMC emergency medicine · 2026Observational
- Article
- Trajectories of chronic multimorbidity patterns in older patients: MTOP study.BMC geriatrics · 2024Observational
- Assessing the relationship between multimorbidity, NCD configurations, frailty phenotypes, and mortality risk in older adults.BMC geriatrics · 2024Article
- Development and feasibility of a conceptual model for planning individualised physical exercise training (BMJ open · 2024Article
- Influences of specialty identity when implementing a new emergency department in Denmark: a qualitative study.BMC health services research · 2024Article
- Multimorbidity clusters in adults 50 years or older with and without a history of cancer: National Health Interview Survey, 2018.BMC geriatrics · 2024Article
- Multimorbidity patterns and disability and healthcare use in Europe: do the associations change with the regional socioeconomic status?European journal of ageing · 2024Article
- Multimorbidity and determinants for initiating outpatient trajectories: A population-based study.BMC public health · 2023Article
- Associations between multimorbidity and frailty transitions among older Americans.Journal of cachexia, sarcopenia and muscle · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe majority of acutely admitted older medical patients are multimorbid, receive multiple drugs, and experience a complex treatment regime. To be able to optimize treatment and care, we need more knowledge of the association between different patterns of multimorbidity and healthcare utilization and the complexity thereof. The purpose was therefore to investigate patterns of multimorbidity in a Danish national cohort of acutely hospitalized medical patients aged 65 and older and to determine the association between these multimorbid patterns with the healthcare utilization and complexity. PATIENTS AND
methodsLongitudinal cohort study of 129,900 (53% women) patients. Latent class analysis (LCA) was used to develop patterns of multimorbidity based on 22 chronic conditions ascertained from Danish national registers. A latent class regression was used to test for differences in healthcare utilization and healthcare complexity among the patterns measured in the year leading up to the index admission.
resultsLCA identified eight distinct multimorbid patterns. Patients belonging to multimorbid patterns including the major chronic conditions; diabetes and chronic obstructive pulmonary disease was associated with higher odds of healthcare utilization and complexity than the reference pattern ("Minimal chronic conditions"). The pattern with the highest number of chronic conditions did not show the highest healthcare utilization nor complexity.
conclusionOur study showed that chronic conditions cluster together and that these patterns differ in healthcare utilization and complexity. Patterns of multimorbidity have the potential to be used in epidemiological studies of healthcare planning but should be confirmed in other population-based studies.
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