ArticleProceedings of the National Academy of Sciences of the United States of America2020
Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
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Who cites it
33 citing papers in PubMed, 55 citations in OpenAlex.
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- Integrated metabolomic and cytokine profiling reveals biomarkers across the clinical spectrum of lupus nephritis.Frontiers in immunology · 2026Article
- Interleukin-10 at the crossroads of immunity in TLR7-induced lupus.Frontiers in immunology · 2026Article
- Interleukin-10 family cytokines: key regulators and novel therapeutic targets for respiratory diseases.Inflammopharmacology · 2025Review
- The fourth trimester and challenges for the lupus patient.EULAR rheumatology open · 2025Review
- Rewired type I IFN signaling is linked to age-dependent differences in COVID-19.Cell reports. Medicine · 2025Article
- Cytokine networks and therapeutic advances in systemic lupus erythematosus.Frontiers in immunology · 2025Review
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- Brain-immune interactions: implication for cognitive impairments in Alzheimer's disease and autoimmune disorders.Journal of leukocyte biology · 2024Review
- Occurrence and role of Tph cells in various renal diseases.Molecular medicine (Cambridge, Mass.) · 2024Review
- Potential of resveratrol in the treatment of systemic lupus erythematosus (Review).Molecular medicine reports · 2024Review
- Cytokines in Follicular Helper T Cell Biology in Physiologic and Pathologic Conditions.Immune network · 2024Review
- T follicular helper cells and T follicular regulatory cells in autoimmune diseases.Frontiers in immunology · 2023Review
- Article
- Salivary IgA subtypes as novel disease biomarkers in systemic lupus erythematosus.Frontiers in immunology · 2023Article
- Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1/2a, single-arm study.Signal transduction and targeted therapy · 2022Article
Corrections and comments
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Authors and funding
29 authors at 8 institutions in 5 countries.
F FacciottiAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
P LarghiAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
R BosottiAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
C VascoAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
N GaglianiSection of Molecular Immunology and Gastroenterology, Center of Internal Medicine, I. Department of Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
C CordiglieriImmunology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.ORCID 0000-0002-2013-0043
S MazzaraIntegrative Biology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
V RanzaniIntegrative Biology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
E RottoliInstitute for Research in Biomedicine, 6500 Bellinzona, Switzerland.
S CurtiIntegrative Biology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
A PenattiAzienda Socio Sanitaria Territoriale Gaetano Pini, 20122 Milan, Italy.
B KarnaniAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
Y KobayashiDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT 06520.
M CrostiAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
M BombaciImmunology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
J P van HamburgDepartment of Rheumatology and Clinical Immunology, Amsterdam University Medical Center (UMC), University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
G RossettiIntegrative Biology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.ORCID 0000-0001-6361-311X
R GualtierottiAzienda Socio Sanitaria Territoriale Gaetano Pini, 20122 Milan, Italy.
M GerosaAzienda Socio Sanitaria Territoriale Gaetano Pini, 20122 Milan, Italy.
S GattiFondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
S TorrettaFondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
L PignataroFondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Cà Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
S W TasDepartment of Rheumatology and Clinical Immunology, Amsterdam University Medical Center (UMC), University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
S AbrignaniImmunology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.ORCID 0000-0002-0794-3285
M PaganiIntegrative Biology Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy.
F GrassiInstitute for Research in Biomedicine, 6500 Bellinzona, Switzerland.
P L MeroniAzienda Socio Sanitaria Territoriale Gaetano Pini, 20122 Milan, Italy.
R A FlavellDepartment of Immunobiology, School of Medicine, Yale University, New Haven, CT 06520.
J GeginatAutoimmunity Laboratory, National Institute of Molecular Genetics "Romeo ed Enrica Invernizzi," 20122 Milan, Italy; geginat@ingm.org.ORCID 0000-0003-4813-0384
Istituto Nazionale Genetica Molecolare · ITUniversity of Milan · ITAzienda Socio Sanitaria Territoriale Lariana · ITUniversity Medical Center · USFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITHoward Hughes Medical Institute · USKarolinska University Hospital · SEYale University · US
Funding
Howard Hughes Medical Institute
Abstract
Interleukin 10 (IL-10) is an antiinflammatory cytokine, but also promotes B cell responses and plays a pathogenic role in systemic lupus erythematosus (SLE). CD4
Indexed as
AdultAnimalsAntibody FormationB-LymphocytesChildCytokinesHumansInterleukin-10Interleukin-17Lupus Erythematosus, SystemicMiceMice, Inbred C57BLPalatine TonsilReceptors, CCR6Th17 CellsT-Lymphocytes, Helper-InducerCCR6 protein, humanCCR6 protein, mouseCytokinesIL10 protein, humanIL10 protein, mouseInterleukin-10Interleukin-17Receptors, CCR6B cell helpinterleukin-10lupus
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.