Evidence map›Paper›PMID 32184315›Full record

ArticleBMJ open2020

Pain Squad+ smartphone app to support real-time pain treatment for adolescents with cancer: protocol for a randomised controlled trial.

Lindsay Jibb, Paul C Nathan, Vicky Breakey, Conrad Fernandez, Donna Johnston, Victor Lewis, Sarah McKillop, Serina Patel, Christine Sabapathy, Caron Strahlendorf and 11 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03632343 (The Pain Squad+ Smartphone App To Support Real-Time Pain Management for Adolescents With Cancer), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03632343 nacompletednot on this map

The Pain Squad+ Smartphone App To Support Real-Time Pain Management for Adolescents With Cancer: A Randomized Controlled Trial

TypeinterventionalSponsorThe Hospital for Sick ChildrenRan2019 to 2025Enrolled102ConditionsTherapy-Associated CancerArmsPain Squad+ with Nurse Support, Pain Squad+
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. e-PainSupport: A Digital Pain Management Application for Home Hospice Care.The American journal of hospice & palliative care · 2024
    Article
  5. The art of nursing in the fourth industrial revolution: Lessons learned.Asia-Pacific journal of oncology nursing · 2024
    Article
  6. Article
  7. Article
  8. Reducing pain in children with cancer at home: a feasibility study of the KLIK pain monitor app.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 13 institutions in 3 countries.

Lindsay JibbChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada lindsay.jibb@sickkids.ca.ORCID 0000-0001-6995-2825
Paul C NathanChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Vicky BreakeyDivision of Hematology/Oncology, McMaster Children's Hospital, Hamilton, Ontario, Canada.
Conrad FernandezFaculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
Donna JohnstonDivision of Hematology/Oncology, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Victor LewisDivision of Hematology/Oncology, Alberta Children's Hospital, Calgary, Alberta, Canada.
Sarah McKillopDivision of Hematology/Oncology, Stollery Children's Hospital, Edmonton, Alberta, Canada.
Serina PatelDivision of Hematology/Oncology, London Health Sciences Centre Children's Hospital, London, Ontario, Canada.
Christine SabapathyDivision of Hematology/Oncology, Montreal Children's Hospital, Montreal, Quebec, Canada.
Caron StrahlendorfDivision of Hematology/Oncology, BC Children's Hospital, Vancouver, BC, Canada.
J Charles VictorInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
Myla E MorettiChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Cynthia NguyenChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Amos HundertChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Celia CassianiChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Graziella El-Khechen RichandiChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Hayley InsullFaculty of Medicine, McGill University, Montreal, Quebec, Canada.
Rachel HamiltonChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Geoffrey FangDivision of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
Susan KuczynskiOntario Parents Advocating for Children with Cancer, Toronto, Ontario, Canada.
Jennifer StinsonChild Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.
Great Ormond Street Hospital · GBBloomberg (United States) · USUniversity of Toronto · CACanadian Partnership Against Cancer · CADalhousie University · CAFaculty (United Kingdom) · GBMcMaster Children's Hospital · CAMontreal Children's Hospital · CAUniversity of Alberta · CAUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Ottawa · CAWestern University · CA

Funding

CIHR PJT-156368
6 · The paper itself

Abstract

introductionPain negatively affects the health-related quality of life (HRQL) of adolescents with cancer. The Pain Squad+ smartphone-based application (app), has been developed to provide adolescents with real-time pain self-management support. The app uses a validated pain assessment and personalised pain treatment advice with centralised decision support via a registered nurse to enable real-time pain treatment in all settings. The algorithm informing pain treatment advice is evidence-based and expert-vetted. This trial will longitudinally evaluate the impact of Pain Squad+, with or without the addition of nurse support, on adolescent health and cost outcomes. METHODS AND ANALYSIS: This will be a pragmatic, multicentre, waitlist controlled, 3-arm parallel-group superiority randomised trial with 1:1:1 allocation enrolling 74 adolescents with cancer per arm from nine cancer centres. Participants will be 12 to 18 years, English-speaking and with ≥3/10 pain. Exclusion criteria are significant comorbidities, end-of-life status or enrolment in a concurrent pain study. The primary aim is to determine the effect of Pain Squad+, with and without nurse support, on pain intensity in adolescents with cancer, when compared with a waitlist control group. The secondary aims are to determine the immediate and sustained effect over time of using Pain Squad+, with and without nurse support, as per prospective outcome measurements of pain interference, HRQL, pain self-efficacy and cost. Linear mixed models with baseline scores as a covariate will be used. Qualitative interviews with adolescents from all trial arms will be conducted and analysed. ETHICS AND DISSEMINATION: This trial is approved by the Hospital for Sick Children Research Ethics Board. Results will provide data to guide adolescents with cancer and healthcare teams in treating pain. Dissemination will occur through partnerships with stakeholder groups, scientific meetings, publications, mass media releases and consumer detailing. TRIAL REGISTRATION NUMBER: NCT03632343 (

Indexed as

Mobile ApplicationsNeoplasmsPainPain ManagementSelf-ManagementSmartphoneAdolescentChildEquivalence Trials as TopicFemaleHumansMaleMulticenter Studies as TopicPain MeasurementPragmatic Clinical Trials as TopicRandomized Controlled Trials as Topiccancerpainpediatricsprotocolrandomised controlled trialsmartphone appsupportive caresymptom treatment

Identifiers

PMID32184315
PMCPMC7076249
OpenAlexW3172975547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.