Evidence map›Paper›PMID 32184299›Full record

ArticleeNeuro

Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior.

Georgia Buscaglia, Kyle R Northington, Jeffrey K Moore, Emily Anne Bates

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 34 citations in OpenAlex.

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  9. Neurochemical atlas of the rabbit spinal cord.Brain structure & function · 2024
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  17. Article
  18. Novel loss of function mutation inFrontiers in cellular neuroscience · 2023
    Article
  19. Article
  20. Multiple roles for the cytoskeleton in ALS.Experimental neurology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Georgia BuscagliaDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045.ORCID 0000-0002-9410-1966
Kyle R NorthingtonDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045.ORCID 0000-0002-8734-074X
Jeffrey K MooreDepartment of Cell and Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Emily Anne BatesDepartment of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora CO 80045 emily.bates@cuanschutz.edu.
University of Colorado Anschutz Medical Campus · US

Funding

Neuroscience Training GrantT32NS099042 · NINDS · UNIVERSITY OF COLORADO DENVER · PI Nidia Calero, GIDON S FELSEN · 2016 to 2026
$2.1M
Regulation of Microtubule Function by Tubulin Carboxy-terminal TailsR01GM112893 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MOORE, JEFFREY KYLE · 2015 to 2019
$1.5M
NIGMS NIH HHS R01 GM112893NINDS NIH HHS T32 NS099042
6 · The paper itself

Abstract

Newly born neurons express high levels of TUBA1A α-tubulin to assemble microtubules for neurite extension and to provide tracks for intracellular transport. In the adult brain,

Indexed as

Mutation, MissenseTubulinAnimalsMiceMicrotubulesNeurogenesisNeuronsTuba1a protein, mouseTubulinataxiamicrotubule networkmovement disordertraffickingTUBA1Atubulin

Identifiers

PMID32184299
PMCPMC7218002
OpenAlexW3010788781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.