Evidence map›Paper›PMID 32184258›Full record

ArticlemBio2020

Feedback Control of a Two-Component Signaling System by an Fe-S-Binding Receiver Domain.

Benjamin J Stein, Aretha Fiebig, Sean Crosson

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Review
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  12. Article
  13. The Protein Quality Control Network inFrontiers in molecular biosciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin J SteinDepartment of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
Aretha FiebigDepartment of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
Sean CrossonDepartment of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA crosson4@msu.edu.ORCID 0000-0002-1727-322X
Michigan State University · US

Funding

Molecular mechanisms controlling stress responses and cell adhesion in bacteriaR35GM131762 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Sean Crosson · 2019 to 2026
$3.2M
Intergrated control of Caulobacter cell physiology by visible light and stressR01GM087353 · NIGMS · UNIVERSITY OF CHICAGO · PI CROSSON, SEAN · 2009 to 2018
$2.8M
Elucidating the mechanism and sensory properties of a novel iron-sulfur binding histidine kinase inhibitorF32GM128283 · NIGMS · UNIVERSITY OF CHICAGO · PI STEIN, BENJAMIN J · 2018 to 2019
$123k
NIGMS NIH HHS F32 GM128283NIGMS NIH HHS R01 GM087353NIGMS NIH HHS R35 GM131762
6 · The paper itself

Abstract

Two-component signaling systems (TCSs) function to detect environmental cues and transduce this information into a change in transcription. In its simplest form, TCS-dependent regulation of transcription entails phosphoryl-transfer from a sensory histidine kinase to its cognate DNA-binding receiver protein. However, in certain cases, auxiliary proteins may modulate TCSs in response to secondary environmental cues.

Indexed as

Signal TransductionBacterial ProteinsCaulobacter crescentusGene Expression Regulation, BacterialHemeHistidine KinaseHomeostasisIronKineticsPhosphorylationSulfurBacterial ProteinsHemeHistidine KinaseIronSulfurCaulobacter crescentusfeedback inhibitionFe-SFixLFixThypoxiakinase inhibitorlonproteasesreceiver domaintwo-component regulatory systems

Identifiers

PMID32184258
PMCPMC7078487
OpenAlexW3012231976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.