ArticlemBio2020
Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance.
Open access · goldAbstract read
In one paragraph
Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Oxidative stress-responsive cell wall remodeling depends on phosphate in Candida albicans.Nature communications · 2026Article
- Cascading damage toProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Phosphate Acquisition in Protozoan Parasites: Transport Systems, and Extracellular Phosphate-Releasing Enzymatic Activities.International journal of molecular sciences · 2026Review
- Targeting calcineurin: a synergistic strategy with caspofungin to induce farnesol-mediated quorum sensing in Nakaseomyces glabrata-an inoculum-dependent tale.The Biochemical journal · 2025Article
- Plants, fungi, and antifungals: A little less talk, a little more action.PLoS pathogens · 2025Article
- Resilience in Resistance: The Role of Cell Wall Integrity in Multidrug-Resistant Candida.Journal of fungi (Basel, Switzerland) · 2025Review
- Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity.PLoS genetics · 2024Article
- Review
- Article
- Phosphate availability conditions caspofungin tolerance, capsule attachment and titan cell formation inFrontiers in fungal biology · 2024Article
- Glycerophosphocholine provision rescuesmSphere · 2023Article
- The Extracellular Vesicles Containing Inorganic Polyphosphate ofJournal of xenobiotics · 2023Article
- The Metabolism of Susceptibility: Clearing the FoG Between Tolerance and Resistance inCurrent clinical microbiology reports · 2023Article
- Stress- and metabolic responses of Candida albicans require Tor1 kinase N-terminal HEAT repeats.PLoS pathogens · 2022Article
- The phosphate language of fungi.Trends in microbiology · 2022Review
- A unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation.PLoS genetics · 2021Article
- Integrative Metabolomics to Identify Molecular Signatures of Responses to Vaccines and Infections.Metabolites · 2020Review
- Phosphate in Virulence ofJournal of fungi (Basel, Switzerland) · 2020Review
- FDA Approved Drug Library Screening Identifies Robenidine as a Repositionable Antifungal.Frontiers in microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Ning-Ning Liu *Division of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Maikel Acosta-Zaldívar *Division of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-9562-6887
Wanjun Qi *Division of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-4593-5734
Joann Diray-Arce *Division of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0003-2183-4269
Louise A WalkerAberdeen Fungal Group, Institute of Medical Sciences, Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen, United Kingdom.ORCID 0000-0002-2236-8776
Theodore J KottomThoracic Diseases Research Unit, Departments of Medicine and Biochemistry, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Rachel KellyChanning Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Min YuanDivision of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
John M AsaraDivision of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Jessica Ann Lasky-SuChanning Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Ofer LevyDivision of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Andrew H LimperThoracic Diseases Research Unit, Departments of Medicine and Biochemistry, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
Neil A R GowMedical Research Council Centre for Medical Mycology at the University of Aberdeen, Institute of Medical Sciences, Aberdeen, United Kingdom.
Julia R KöhlerDivision of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA julia.koehler@childrens.harvard.edu.
Boston Children's Hospital · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USMayo Clinic · USUniversity of Aberdeen · GB
Funding
Transcriptomics to define biomarkers of neonatal vaccine immunogenicityU19AI118608 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI LEVY, OFER · 2017 to 2021
$24.7MMulti-Omic Endotyping of AsthmaK01HL146980 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KELLY, RACHEL SABINE · 2019 to 2023
$891kRole of Candida albicans phosphate transport in cell wall maintenance and echinocandin toleranceR21AI137716 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI KOEHLER, JULIA R · 2018 to 2019
$487kMedical Research Council MR/N006364/1Medical Research Council MR/N006364/2NHLBI NIH HHS K01 HL146980NIAID NIH HHS R21 AI137716NIAID NIH HHS U19 AI118608Wellcome Trust
Abstract
The
Indexed as
Candida albicansCell WallFungal PolysaccharidesFungal ProteinsMetabolomicsPhosphatesFungal PolysaccharidesFungal ProteinsPhosphatesantifungal agentsCandida albicanscell wallchitin synthaseglucan synthasenucleotide sugarPho84phosphate metabolism
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.