Evidence map›Paper›PMID 32184249›Full record

ArticlemBio2020

Metabolite Sequestration Enables Rapid Recovery from Fatty Acid Depletion in Escherichia coli.

Christopher J Hartline, Ahmad A Mannan, Di Liu, Fuzhong Zhang, Diego A Oyarzún

Abstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. EnhancingApplied and environmental microbiology · 2025
    Article
  3. Article
  4. (p)ppGpp mediates persister formation inFrontiers in microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Opportunities at the Interface of Network Science and Metabolic Modeling.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christopher J Hartline *Department of Energy, Environmental & Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0002-6030-911X
Ahmad A Mannan *Warwick Integrative Synthetic Biology Centre & School of Engineering, University of Warwick, Coventry, United Kingdom.ORCID 0000-0001-7628-8416
Di LiuDepartment of Energy, Environmental & Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA.ORCID 0000-0002-7484-5810
Fuzhong ZhangDepartment of Energy, Environmental & Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA fzhang@seas.wustl.edu d.oyarzun@ed.ac.uk.ORCID 0000-0001-6979-7909
Diego A OyarzúnSchool of Informatics, University of Edinburgh, Edinburgh, United Kingdom fzhang@seas.wustl.edu d.oyarzun@ed.ac.uk.ORCID 0000-0002-0381-5278

Funding

Wellcome Trust
6 · The paper itself

Abstract

Microbes adapt their metabolism to take advantage of nutrients in their environment. Such adaptations control specific metabolic pathways to match energetic demands with nutrient availability. Upon depletion of nutrients, rapid pathway recovery is key to release cellular resources required for survival under the new nutritional conditions. Yet, little is known about the regulatory strategies that microbes employ to accelerate pathway recovery in response to nutrient depletion. Using the fatty acid catabolic pathway in

Indexed as

Adaptation, PhysiologicalEscherichia coliFatty AcidsKineticsMetabolic EngineeringMetabolic Networks and PathwaysModels, TheoreticalNutrientsFatty AcidsNutrientsmetabolic dynamicsmetabolic regulationsynthetic biologytranscription factor

Identifiers

PMID32184249
PMCPMC7078478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.