ArticleJournal of diabetes and its complications2020
Characteristics of the microbiota in the urine of women with type 2 diabetes.
Article in Journal of diabetes and its complications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- The urinary microbiome in association with diabetes and diabetic kidney disease: A systematic review.PloS one · 2025Pooled it
- Alterations in urinary microbiota composition and function in men with Asthenozoospermia: a case-control study.Basic and clinical andrology · 2026Article
- Precision Microbiome Modulation: Exploring Lactobacillus spp. as A Targeted Strategy for Type 2 Diabetes Management.Current nutrition reports · 2026Review
- In-depth Microbiological Characterization of Urine From Subjects With Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2024Article
- Draft genome assemblies of oneMicrobiology resource announcements · 2024Article
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- Draft genome sequences of threeMicrobiology resource announcements · 2024Article
- Draft genome sequences ofMicrobiology resource announcements · 2024Article
- Draft genome sequences of fiveMicrobiology resource announcements · 2024Article
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- Effect of mastectomy on gut microbiota and its metabolites in patients with breast cancer.Frontiers in microbiology · 2024Article
- Impact of coexisting type 2 diabetes mellitus on the urinary microbiota of kidney stone patients.PeerJ · 2024Article
- Application of machine learning tools: Potential and useful approach for the prediction of type 2 diabetes mellitus based on the gut microbiome profile.Experimental and therapeutic medicine · 2022Article
- UPΦ phages, a new group of filamentous phages found in several members ofVirus evolution · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe urinary microbiota in women with type 2 diabetes (T2DM) can have bacterial uropathogens which are more virulent. The primary objective was to describe and compare the characteristics of the microbiota in voided urine of women with and without T2DM.
methodsTwo cohorts of women: those with T2DM (n = 87) and those without T2DM (n = 49) were studied. Demographic data, hemoglobin A1c (HbA1c), fasting serum glucose, and voided urine were collected. To determine the characteristics of the microbiota in the urine, 16S rRNA gene sequencing was used.
resultsThe genus Lactobacillus was more often present in women with T2DM (75.9%, n = 66) than in the controls (59.2%, n = 30) (p = 0.042), as was the family Enterobacteriaceae (12.6% T2DM versus 2.0% control, p = 0.055). There was evidence of an association between HbA1c and the relative abundance of the various bacteria in the total cohort. The relative abundance of Lactobacillus was positively associated (ρ = 0.19, 95% CI: 0.02, 0.34), while Corynebacterium (ρ = -0.26, 95% CI: -0.41, -0.10) and Prevotella (ρ = -0.23, 95% CI: -0.38, -0.06) were inversely associated with HbA1c.
conclusionsEnterobacteriaceae (e.g. E. coli) predispose women to urinary tract infections and since T2DM increases this risk, further study is needed. The species of Lactobacillus and its impact needs exploration.
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