Evidence map›Paper›PMID 32183948›Full record

ReviewCancer cell2020

m

Huilin Huang, Hengyou Weng, Jianjun Chen

Open access · bronzeAbstract readReview
In one paragraph

Review in Cancer cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 815 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
815citing papers in PubMed, 1 pooled it
73.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

815 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,290 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. ERa-induced mBritish journal of cancer · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. ACSL4-Dependent Lysosomal Lipid Peroxidation Links WTAP-Mediated mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. METTL3-YTHDF1-driven mMolecular and cellular biochemistry · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. TRMT6-Mediated mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  18. Epitranscriptomic Analysis of A-to-I RNA Editing and mInternational journal of molecular sciences · 2026
    Review
  19. mPharmaceuticals (Basel, Switzerland) · 2026
    Review
  20. Article

755 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Huilin HuangDepartment of Systems Biology & the Gehr Family Center for Leukemia Research, the Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA; Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Hengyou WengDepartment of Systems Biology & the Gehr Family Center for Leukemia Research, the Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA; Guangzhou Regenerative Medicine and Health Guangdong Laboratory (GRMH-GDL), Guangzhou 510005, China.
Jianjun ChenDepartment of Systems Biology & the Gehr Family Center for Leukemia Research, the Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA. Electronic address: jianchen@coh.org.
City of Hope · USGuangzhou Regenerative Medicine and Health Guangdong Laboratory · CNSun Yat-sen University · CN

Funding

Targeting FTO to treat acute myeloid leukemiaR01CA243386 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2020 to 2024
$2.8M
The role and mechanism of METTL3/METTL14-mediated RNA modification in the pathogenesis and drug-resistance of AMLR01CA236399 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2019 to 2023
$2.3M
Targeting TET1 signaling to treat acute myeloid leukemiaR01CA211614 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.3M
The function and underlying mechanism of TET1 in myelodysplastic syndromesR01DK124116 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2020 to 2023
$2.2M
The role and mechanism of FTO in leukemogenesis and drug responseR01CA214965 · NCI · UNIVERSITY OF CINCINNATI · PI CHEN, JIANJUN · 2017 to 2021
$2.1M
The role, mechanism and therapeutic potential of TET1 in MDSR56DK120282 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI CHEN, JIANJUN · 2018 to 2018
$100k
NCI NIH HHS R01 CA211614NCI NIH HHS R01 CA214965NCI NIH HHS R01 CA236399NCI NIH HHS R01 CA243386NIDDK NIH HHS R01 DK124116NIDDK NIH HHS R56 DK120282
6 · The paper itself

Abstract

N

Indexed as

RNA, MessengerRNA, UntranslatedAdenosineEpigenesis, GeneticFemaleGene Expression RegulationGene Expression Regulation, NeoplasticHumansImmunotherapyMaleMutationNeoplasmsAdenosineN-methyladenosineRNA, MessengerRNA, Untranslatedcancer epigeneticscancer stem cellsdrug resistanceepitranscriptomeimmune therapyN(6)-methyladenosine (m(6)A)non-coding RNAprognosisRNA modificationtargeted therapeutics

Identifiers

PMID32183948
PMCPMC7141420
OpenAlexW3011765028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.