Evidence map›Paper›PMID 32183812›Full record

ArticleBMC complementary medicine and therapies2020

Gas chromatography-mass spectrometry analysis, phytochemical screening and antiprotozoal effects of the methanolic Viola tricolor and acetonic Laurus nobilis extracts.

Gaber El-Saber Batiha, Amany Magdy Beshbishy, Luay Alkazmi, Oluyomi Stephen Adeyemi, Eman Nadwa, Eman Rashwan, Amany El-Mleeh, Ikuo Igarashi

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  3. Article
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  6. Article
  7. Review
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  9. Article
  10. Article
  11. Isolation ofFoods (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Chemotherapeutic Potential ofAntibiotics (Basel, Switzerland) · 2020
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gaber El-Saber BatihaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan. dr_gaber_batiha@vetmed.dmu.edu.eg.ORCID http://orcid.org/0000-0002-7817-425X
Amany Magdy BeshbishyNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.
Luay AlkazmiBiology department, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Oluyomi Stephen AdeyemiMedicinal Biochemistry, Nanomedicine and Toxicology Laboratory, Department of Biochemistry, Landmark University, Omu-Aran, Kwara State, 251101, Nigeria.
Eman NadwaDepartment of Pharmacology and Therapeutics, College of Medicine, Jouf University, Sakaka, Saudi Arabia.
Eman RashwanDepartment of Physiology, College of Medicine, Al-Azhar University, Assuit, Egypt.
Amany El-MleehDepartment of Pharmacology, Faculty of Veterinary Medicine, Menoufia University, Shibin El Kom, Egypt.
Ikuo IgarashiNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan.

Funding

This study was supported by the Ministry of Higher Education Egypt, the Japanese Society for the Promotion of Science, and the Ministry of Education, Culture, Sports, Science and Technology, Japan (JSPS) 18H02337
6 · The paper itself

Abstract

backgroundThe antiprotozoal and antioxidant activities of Viola tricolor and Laurus nobilis have been reported recently. Thus, the existing study pursued to assess the growth inhibition effect of methanolic extract of V. tricolor (MEVT) and acetonic extract of L. nobilis (AELN) against five Babesia parasites and Theileria equi in vitro and in vivo.

resultsMEVT and AELN suppressed Babesia bovis, B. bigemina, B. divergens, B. caballi, and T. equi growth at half-maximal inhibitory concentration (IC

conclusionsThese analyses indicate the prospects of MEVT and AELN as good candidates for isolating new anti-protozoal compounds which could assist in the development of new drug molecules with new drug targets.

Indexed as

AcetoneAntiprotozoal AgentsBabesiaGas Chromatography-Mass SpectrometryLaurusMethanolPhytochemicalsPlant ExtractsTheileriaViolaAcetoneAntiprotozoal AgentsMethanolPhytochemicalsPlant ExtractsDrug discoveryMedicinal biochemistryNatural productsParasitic diseases

Identifiers

PMID32183812
PMCPMC7077018

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.