Evidence map›Paper›PMID 32183762›Full record

ArticleBMC public health2020

The role of family factors in antiretroviral therapy (ART) adherence self-efficacy among HIV-infected adolescents in southern Uganda.

Proscovia Nabunya, Ozge Sensoy Bahar, Bin Chen, Daji Dvalishvili, Christopher Damulira, Fred M Ssewamala

Registry-linked trialAbstract read
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01790373 (Suubi+Adherence), which is not on this map. Cited by 39 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01790373 naactive not recruitingnot on this map

Suubi+Adherence: Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence

TypeinterventionalSponsorWashington University School of MedicineRan2013 to 2026Enrolled702ConditionsHIVArmsSuubi+Adherence, Bolstered Standard of Care
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  9. Barriers to Antiretroviral Therapy Adherence Among Children in Ekurhuleni, South Africa: A Descriptive Study.International journal of environmental research and public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Proscovia NabunyaWashington University in St. Louis, Brown School of Social Work, One Brookings Drive, St. Louis, MO, 63130, USA. nabunyap@wustl.edu.ORCID http://orcid.org/0000-0002-9088-5839
Ozge Sensoy BaharWashington University in St. Louis, St. Louis, MO, USA.
Bin ChenWashington University in St. Louis, St. Louis, MO, USA.
Daji DvalishviliWashington University in St. Louis, St. Louis, MO, USA.
Christopher DamuliraInternational Center for Child Health and Development, Masaka, Uganda.
Fred M SsewamalaWashington University in St. Louis, St. Louis, MO, USA.

Funding

Suubi+Adherence-R2: Examining the longitudinal HIV treatment adherence among youth living with HIV (YLHIV) transitioning into young adulthoodR01HD074949 · NICHD · WASHINGTON UNIVERSITY · PI NABUNYA, PROSCOVIA, SENSOY BAHAR, OZGE · 2012 to 2024
$7.7M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Strengthening Child Health Research Capacity in Resource Constrained Settings: Researcher Resilience Training (RRT)R25MH118935 · NIMH · WASHINGTON UNIVERSITY · PI SEAN JOE, Mary McKernan McKay · 2018 to 2026
$1.5M
National Institute of Child Health and Human Development R01HD074949NICHD NIH HHS R01 HD074949NICHD NIH HHS R25 HD045810NIMH NIH HHS R25 MH067127NIMH NIH HHS R25 MH118935
6 · The paper itself

Abstract

backgroundAdolescents living with HIV in sub-Saharan Africa are a vulnerable group at the intersection of poverty and health disparities. The family is a vital microsystem that provides financial and emotional support to achieve optimal antiretroviral therapy (ART) adherence. In this study, we explore the association between family factors and ART adherence self-efficacy, a significant psychological concept playing a critical role in ART adherence.

methodsData from an NIH-funded study called Suubi + Adherence, an economic empowerment intervention for HIV positive adolescents (average age = 12.4 years) in southern Uganda was analyzed. We conducted multilevel regression analyses to explore the protective family factors, measured by family cohesion, child-caregiver communication and perceived child-caregiver support, associated with ART adherence self-efficacy.

resultsThe average age was 12.4 years and 56.4% of participants were female. The average household size was 5.7 people, with 2.3 children> 18 years. Controlling for sociodemographic and household characteristics, family cohesion (β = 0.397, p = 0.000) and child-caregiver communication (β = 0.118, p = 0.026) were significantly associated with adherence self-efficacy to ART.

conclusionFindings point to the need to strengthen family cohesion and communication within families if we are to enhance adherence self-efficacy among adolescents living with HIV.

trial registrationThis trial was registered with ClinicalTrials.gov (registration number: NCT01790373) on 13 February 2013.

Indexed as

Self EfficacyAdolescentAnti-Retroviral AgentsCaregiversChildFamilyFamily RelationsFemaleHIV InfectionsHumansMaleMedication AdherencePovertyUgandaYoung AdultAnti-Retroviral AgentsAdherence self-efficacyAntiretroviral therapy adherenceFamily cohesionHIV-infected adolescentsSub-Saharan Africa

Identifiers

PMID32183762
PMCPMC7077174

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.