Evidence map›Paper›PMID 32183497›Full record

ArticleAnimals : an open access journal from MDPI2020

The Prophylactic Use of Bovine Colostrum in a Murine Model of TNBS-Induced Colitis.

Laura Menchetti, Giulio Curone, Iulia Elena Filipescu, Olimpia Barbato, Leonardo Leonardi, Gabriella Guelfi, Giovanna Traina, Patrizia Casagrande-Proietti, Federica Riva, Anna Beatrice Casano and 4 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Colostrum Quality in Different Goat Breeds Reared in Northern Italy.Animals : an open access journal from MDPI · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Laura MenchettiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0001-8500-7970
Giulio CuroneDepartment of Veterinary Medicine, University of Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0001-6352-0036
Iulia Elena FilipescuL'Arca Veterinary Clinic, Viale Antonio Gramsci, 141/E, Cortona, 52044 Arezzo, Italy.
Olimpia BarbatoDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0003-0828-4610
Leonardo LeonardiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0003-1382-9275
Gabriella GuelfiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0003-3695-9275
Giovanna TrainaDepartment of Pharmaceutical Sciences, University of Perugia, Via A. Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0001-9996-3584
Patrizia Casagrande-ProiettiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.
Federica RivaDepartment of Veterinary Medicine, University of Milano, Via dell'Università 6, 26900 Lodi, Italy.
Anna Beatrice CasanoDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.
Federica PiroDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Via Elce di Sotto 8, 06123 Perugia, Italy.
Daniele VigoDepartment of Veterinary Medicine, University of Milano, Via dell'Università 6, 26900 Lodi, Italy.ORCID 0000-0002-6292-4992
Alda QuattroneDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.
Gabriele BrecchiaDepartment of Veterinary Medicine, University of Milano, Via dell'Università 6, 26900 Lodi, Italy.
University of Perugia · ITUniversity of Milan · ITAzienda Usl 8 Arezzo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of a short-term administration of bovine colostrum (BC) in a TNBS model of induced colitis. Colitis was induced by TNBS treatment after seven days of BC (BC group, n = 12) or saline (control group, n = 12) administration in mice. Clinical signs, histopathological characteristics, expression levels of Toll-like receptor 4 (TLR4), pro- and anti-inflammatory cytokines, and microbial composition were assessed. BC was well tolerated and did not induce any histological damage or clinical symptoms. After TNBS treatment, the BC group showed a reduction in body weight (BW) loss compared to Control (

Indexed as

bovine colostrumcytokinesmicrobiotaTLR4TNBS-induced colitis

Identifiers

PMID32183497
PMCPMC7143345
OpenAlexW3011454256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.