Evidence map›Paper›PMID 32183492›Full record

ArticleNutrients2020

Micronutrient Deficiencies Following Minimally Invasive Esophagectomy for Cancer.

Henricus J B Janssen, Laura F C Fransen, Jeroen E H Ponten, Grard A P Nieuwenhuijzen, Misha D P Luyer

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Sarcopenia in Colorectal Cancer Surgery-Minimally Invasive vs. Open.Journal of cachexia, sarcopenia and muscle · 2025
    Article
  6. Article
  7. Review
  8. Micronutrient deficiencies and anemia in the follow-up after gastroesophageal cancer surgery.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Article
  9. Review
  10. Article
  11. Nutritional care in patients undergoing laparoscopic/minimally invasive surgeries for gastrointestinal tumours.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023
    Review
  12. Review
  13. Article
  14. Ferroptosis and its Role in Gastric Cancer.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Henricus J B JanssenDepartment of Surgery, Catharina Hospital, Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0001-7684-2624
Laura F C FransenDepartment of Surgery, Catharina Hospital, Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0002-8404-673X
Jeroen E H PontenDepartment of Surgery, Catharina Hospital, Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0003-1517-804X
Grard A P NieuwenhuijzenDepartment of Surgery, Catharina Hospital, Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands.
Misha D P LuyerDepartment of Surgery, Catharina Hospital, Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands.ORCID 0000-0002-9483-1520
Radboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decades, survival rates for patients with resectable esophageal cancer have improved significantly. Consequently, the sequelae of having a gastric conduit, such as development of micronutrient deficiencies, become increasingly apparent. This study investigated postoperative micronutrient trends in the follow-up of patients following a minimally invasive esophagectomy (MIE) for cancer. Patients were included if they had at least one postoperative evaluation of iron, ferritin, vitamins B1, B6, B12, D, folate or methylmalonic acid. Data were available in 83 of 95 patients. Of these, 78.3% (65/83) had at least one and 37.3% (31/83) had more than one micronutrient deficiency at a median of 6.1 months (interquartile range (IQR) 5.4-7.5) of follow-up. Similar to the results found in previous studies, most common deficiencies identified were: iron, vitamin B12 and vitamin D. In addition, folate deficiency and anemia were detected in a substantial amount of patients in this cohort. At 24.8 months (IQR 19.4-33.1) of follow-up, micronutrient deficiencies were still common, however, most deficiencies normalized following supplementation on indication. In conclusion, patients undergoing a MIE are at risk of developing micronutrient deficiencies as early as 6 up to 24 months after surgery and should therefore be routinely checked and supplemented when needed.

Indexed as

Esophageal NeoplasmsEsophagectomyMalnutritionMicronutrientsPostoperative ComplicationsAdultAgedCohort StudiesDietary SupplementsFemaleHumansMaleMiddle AgedNutritional StatusPostoperative PeriodRandomized Controlled Trials as TopicMicronutrientsesophageal canceresophagectomymicronutrient deficienciesvitamin deficiencies

Identifiers

PMID32183492
PMCPMC7146612
OpenAlexW3012270915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.