Evidence map›Paper›PMID 32183431›Full record

ArticleMicromachines2020

Digital Microfluidics for Single Bacteria Capture and Selective Retrieval Using Optical Tweezers.

Phalguni Tewari Kumar, Deborah Decrop, Saba Safdar, Ioannis Passaris, Tadej Kokalj, Robert Puers, Abram Aertsen, Dragana Spasic, Jeroen Lammertyn

Abstract read
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Optical sorting: past, present and future.Light, science & applications · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Analysis ofFrontiers in cellular and infection microbiology · 2023
    Review
  12. Review
  13. Review
  14. Microfluidic Approaches for Affinity-Based Exosome Separation.International journal of molecular sciences · 2022
    Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Phalguni Tewari KumarDepartment of Biosystems, Biosensors Group, KU Leuven, 3001 Leuven, Belgium.
Deborah DecropDepartment of Biosystems, Biosensors Group, KU Leuven, 3001 Leuven, Belgium.
Saba SafdarDepartment of Biosystems, Biosensors Group, KU Leuven, 3001 Leuven, Belgium.
Ioannis PassarisDepartment of Microbial and Molecular Systems, KU Leuven, 3001 Leuven, Belgium.
Tadej KokaljDepartment of Biosystems, Biosensors Group, KU Leuven, 3001 Leuven, Belgium.
Robert PuersESAT-MICAS, Microelectronics and Sensors, KU Leuven, 3001 Leuven, Belgium.
Abram AertsenDepartment of Microbial and Molecular Systems, KU Leuven, 3001 Leuven, Belgium.
Dragana SpasicDepartment of Biosystems, Biosensors Group, KU Leuven, 3001 Leuven, Belgium.
Jeroen LammertynDepartment of Biosystems, Biosensors Group, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0001-8143-6794

Funding

Agentschap voor Innovatie door Wetenschap en Technologie 121615Agentschap voor Innovatie door Wetenschap en Technologie Doctoral fellowshipFonds Wetenschappelijk Onderzoek G080016NH2020 Marie Skłodowska-Curie Actions 675412Onderzoeksraad, KU Leuven DBOF-grantOnderzoeksraad, KU Leuven IDO/10/012Onderzoeksraad, KU Leuven PDM 17-093
6 · The paper itself

Abstract

When screening microbial populations or consortia for interesting cells, their selective retrieval for further study can be of great interest. To this end, traditional fluorescence activated cell sorting (FACS) and optical tweezers (OT) enabled methods have typically been used. However, the former, although allowing cell sorting, fails to track dynamic cell behavior, while the latter has been limited to complex channel-based microfluidic platforms. In this study, digital microfluidics (DMF) was integrated with OT for selective trapping, relocation, and further proliferation of single bacterial cells, while offering continuous imaging of cells to evaluate dynamic cell behavior. To enable this, magnetic beads coated with

Indexed as

digital microfluidicsoptical tweezersSalmonella Typhimuriumsingle-cell

Identifiers

PMID32183431
PMCPMC7142809

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.