Evidence map›Paper›PMID 32183306›Full record

ArticleInternational journal of molecular sciences2020

Isolation and Quantification of Uremic Toxin Precursor-Generating Gut Bacteria in Chronic Kidney Disease Patients.

Tessa Gryp, Geert R B Huys, Marie Joossens, Wim Van Biesen, Griet Glorieux, Mario Vaneechoutte

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Review
  9. Gut-kidney axis: Dysbiosis and renal disease.World journal of nephrology · 2026
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Systemic elevation of gut derivedFrontiers in physiology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tessa GrypDepartment of Internal Medicine and Pediatrics, Nephrology Section, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0003-2939-1351
Geert R B HuysDepartment of Microbiology, Immunology and Transplantation, Molecular Microbiology-Microbiome Research Lab, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7092-4837
Marie JoossensDepartment of Microbiology, Immunology and Transplantation, Molecular Microbiology-Microbiome Research Lab, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-8410-5528
Wim Van BiesenDepartment of Internal Medicine and Pediatrics, Nephrology Section, Ghent University Hospital, 9000 Ghent, Belgium.
Griet GlorieuxDepartment of Internal Medicine and Pediatrics, Nephrology Section, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0002-7641-4707
Mario VaneechoutteDepartment of Diagnostic Sciences, Laboratory Bacteriology Research, Ghent University, 9000 Ghent, Belgium.
Ghent University Hospital · BEKU Leuven · BEGhent University · BE

Funding

Fonds Wetenschappelijk Onderzoek G017815N
6 · The paper itself

Abstract

In chronic kidney disease (CKD), impaired kidney function results in accumulation of uremic toxins, which exert deleterious biological effects and contribute to inflammation and cardiovascular morbidity and mortality. Protein-bound uremic toxins (PBUTs), such as

Indexed as

Amino Acids, AromaticBacteriaCresolsFecesGastrointestinal MicrobiomeHumansIndicanIndoleacetic AcidsRenal Insufficiency, ChronicSulfuric Acid EstersToxins, Biological4-cresol sulfateAmino Acids, AromaticCresolsIndicanindoleacetic acidIndoleacetic AcidsSulfuric Acid EstersToxins, Biologicalaromatic amino acidsbacterial culturebacterial metabolizationchronic kidney diseasefecal bacteriaindoleindole-3-acetic acidp-cresolphenolprotein-bound uremic toxinsqPCR

Identifiers

PMID32183306
PMCPMC7139965
OpenAlexW3010865806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.