Evidence map›Paper›PMID 32183241›Full record

ReviewNon-coding RNA2020

Long Non-coding RNAs Mechanisms of Action in HIV-1 Modulation and the Identification of Novel Therapeutic Targets.

Roslyn M Ray, Kevin V Morris

Open access · goldAbstract readReview
In one paragraph

Review in Non-coding RNA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Plumbing mysterious RNAs in "dark genome" for the conquest of human diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Review
  11. Evaluating lncRNA Expression Patterns during HIV-1 Treatment Interruption.International journal of molecular sciences · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Heliyon · 2021
    Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Roslyn M RayThe Center for Gene Therapy, The Beckman Research Institute, City of Hope Medical Center, Duarte, CA 91010, USA.
Kevin V MorrisThe Center for Gene Therapy, The Beckman Research Institute, City of Hope Medical Center, Duarte, CA 91010, USA.ORCID 0000-0002-0157-0553
City Of Hope National Medical Center · US

Funding

Transcriptional control, targeted modification, and excision of HIV in the brainR01MH113407 · NIMH · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI BURNETT, JOHN CORY · 2017 to 2021
$3.0M
Targeted inhibition of HIV-1 latencyR01AI111139 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI MORRIS, KEVIN V · 2014 to 2018
$2.7M
National Institute of Allergy and Infectious Diseases RO1 AI111139-01NIMH NIH HHS R01 113407-01NIMH NIH HHS R01 MH113407
6 · The paper itself

Abstract

This review aims to highlight the role of long non-coding RNAs in mediating human immunodeficiency virus (HIV-1) viral replication, latency, disease susceptibility and progression. In particular, we focus on identifying possible lncRNA targets and their purported mechanisms of action for future drug design or gene therapeutics.

Indexed as

antisenseepigeneticHIVlncRNAtranscription

Identifiers

PMID32183241
PMCPMC7151623
OpenAlexW3012053601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.