Evidence map›Paper›PMID 32183138›Full record

ArticleBiomolecules2020

Methylation of the Suppressor Gene

Alfonso Tramontano, Francesca Ludovica Boffo, Giusi Russo, Mariarosaria De Rosa, Ilaria Iodice, Antonio Pezone

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. The methylation level of a single cancer risk marker gene reflects methylation burden in gastric mucosa.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2023
    Article
  9. Article
  10. Caloric restriction induced epigenetic effects on aging.Frontiers in cell and developmental biology · 2022
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Overview of current targeted therapy in gallbladder cancer.Signal transduction and targeted therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alfonso TramontanoDepartment of Precision Medicine University of Campania "L. Vanvitelli", 80131 Naples, Italy.ORCID 0000-0003-4985-1087
Francesca Ludovica BoffoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Istituto di Endocrinologia ed Oncologia Sperimentale del C.N.R., Università Federico II, 80131 Napoli, Italy.
Giusi RussoDipartimento di Medicina Molecolare e Biotecnologie Mediche, Istituto di Endocrinologia ed Oncologia Sperimentale del C.N.R., Università Federico II, 80131 Napoli, Italy.
Mariarosaria De RosaDipartimento di Medicina Molecolare e Biotecnologie Mediche, Istituto di Endocrinologia ed Oncologia Sperimentale del C.N.R., Università Federico II, 80131 Napoli, Italy.ORCID 0000-0001-7458-7359
Ilaria IodiceDipartimento di Medicina Molecolare e Biotecnologie Mediche, Istituto di Endocrinologia ed Oncologia Sperimentale del C.N.R., Università Federico II, 80131 Napoli, Italy.
Antonio PezoneDepartment of Precision Medicine University of Campania "L. Vanvitelli", 80131 Naples, Italy.
Institute for Experimental Endocrinology and Oncology · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

Associazione Italiana per la Ricerca sul Cancro 16983 to EVAEpigenomics Flagship Project-EPIGEN, C.N.R. Funding for open access charge: Epigenomics Flagship Project and Fondazione Cariplo Ricerca Biomedica sulle malattie legate all'invecchiamento ref. 2016-1031Fondazione Medicina Molecolare e Terapia Cellulare, Universita' Politecnica delle Marche to EVA
6 · The paper itself

Abstract

Tumor suppressor genes in the

Indexed as

CpG IslandsCyclin-Dependent Kinase Inhibitor p16DNA MethylationDNA ReplicationGene Expression Regulation, NeoplasticPromoter Regions, GeneticCellular SenescenceDNA DamageHeLa CellsHumansCDKN2A protein, humanCyclin-Dependent Kinase Inhibitor p16DNA damage and repairDNA methylationgene expression

Identifiers

PMID32183138
PMCPMC7175352
OpenAlexW3011602268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.