Evidence map›Paper›PMID 32183096›Full record

ArticleInternational journal of molecular sciences2020

Benefit of Later-Time-Point PET Imaging of HER3 Expression Using Optimized Radiocobalt-Labeled Affibody Molecules.

Sara S Rinne, Charles Dahlsson Leitao, Zahra Saleh-Nihad, Bogdan Mitran, Vladimir Tolmachev, Stefan Ståhl, John Löfblom, Anna Orlova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Controlling the Redox Chemistry of Cobalt Radiopharmaceuticals.Angewandte Chemie (International ed. in English) · 2024
    Article
  3. Review
  4. Review
  5. Article
  6. HER3 PET Imaging:Cancers · 2021
    Article
  7. Review
  8. PET and SPECT Imaging of the EGFR Family (RTK Class I) in Oncology.International journal of molecular sciences · 2021
    Review
  9. Scientific reports · 2021
    Article
  10. The Radiolabeled HER3 Targeting Molecules for Tumor Imaging.Iranian journal of pharmaceutical research : IJPR · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Sara S RinneDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Charles Dahlsson LeitaoDepartment of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, 106 91 Stockholm, Sweden.
Zahra Saleh-NihadDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Bogdan MitranDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 85 Uppsala, Sweden.ORCID 0000-0002-6122-1734
Stefan StåhlDepartment of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, 106 91 Stockholm, Sweden.
John LöfblomDepartment of Protein Science, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, 106 91 Stockholm, Sweden.ORCID 0000-0001-9423-0541
Anna OrlovaDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0001-6120-2683
Uppsala University · SEKTH Royal Institute of Technology · SE

Funding

Cancerfonden CAN2016/463Cancerfonden CAN 2017/425Cancerfonden CAN2017/649Cancerfonden CAN 2018/436Cancerfonden CAN2019/190101Vetenskapsrådet 2015-02509Vetenskapsrådet 2019-00994VINNOVA 2019/00104
6 · The paper itself

Abstract

HER3-binding affibody molecules are a promising format for visualization of HER3 expression. Cobalt-55, a positron-emitting isotope, with a half-life of 17.5 h, allows for next-day imaging. We investigated the influence of the charge of the radiocobalt-chelator complex on the biodistribution of anti-HER3 affibody molecule (HE)

Indexed as

AcetatesAnimalsAntibodiesCell Line, TumorCobalt RadioisotopesFemaleHeterocyclic Compounds, 1-RingHumansMiceMice, Inbred BALB CMice, NudeNeoplasms, ExperimentalPositron-Emission TomographyProtein BindingRadiopharmaceuticalsReceptor, ErbB-31-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidAcetatesAntibodiesCobalt RadioisotopesErbB3 protein, mouseHeterocyclic Compounds, 1-RingRadiopharmaceuticalsReceptor, ErbB-3affibodycobalt-55DOTADOTAGAgallium-68HER3NODAGANOTAPETradiocobalt

Identifiers

PMID32183096
PMCPMC7139902
OpenAlexW3011005037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.