Evidence map›Paper›PMID 32183093›Full record

ReviewInternational journal of molecular sciences2020

Physiologic Events of Embryo Implantation and Decidualization in Human and Non-Human Primates.

Maria Ariadna Ochoa-Bernal, Asgerally T Fazleabas

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05062135 (Abnormalities of the Endometrium Persist Despite Adequate Progesterone Supplementation in the Polycystic Ovary Syndrome), which is not on this map. Cited by 125 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 3 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05062135 nacompletednot on this map

Abnormalities of the Endometrium Persist Despite Adequate Progesterone Supplementation in the Polycystic Ovary Syndrome

TypeinterventionalSponsorUniversity of Sao Paulo General HospitalRan2014 to 2019Enrolled36ConditionsPolycystic Ovary, Progesterone ResistanceArmsProgesterone 400 Mg Vaginal Suppository on PCOS
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 3 syntheses or guidelines pooled it, 293 citations in OpenAlex.

  1. Pooled it
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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maria Ariadna Ochoa-BernalDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0002-9070-7135
Asgerally T FazleabasDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.
Michigan State University · US

Funding

Modulation of the Receptive Endometrium by CGR01HD042280 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FAZLEABAS, ASGERALLY T. · 2003 to 2020
$4.6M
Reproductive and Developmental Sciences Training Program - T32T32HD087166 · NICHD · MICHIGAN STATE UNIVERSITY · PI Ronald L Chandler, Keith E Latham · 2016 to 2026
$2.5M
Eunice Kennedy Shriver National Institute of Child Health and Human Development T32HD087166NICHD NIH HHS R01 HD042280NICHD NIH HHS T32 HD087166NIH HHS HD042280
6 · The paper itself

Abstract

Reproduction is a fundamental process for the preservation of the human species. This process requires a sequence of orchestrated events that are necessary for a successful pregnancy. Two of the most critical steps in the establishment of human pregnancy are implantation and decidualization, which are required for maternal interactions with the developing embryo. This review primarily highlights the physiological aspects of these two events and the adverse pregnancy outcomes from defective implantation and decidualization. The focus of this review is to provide a general concept of the mechanisms involved during the window of implantation, description of components involved in the process and possible pathologies that could disrupt the embryo implantation and decidualization and specifically as it applies to women and non-human primates.

Indexed as

Embryo ImplantationAbortion, HabitualAnimalsDeciduaFemaleHumansMicroRNAsPregnancyPrimatesMicroRNAscytokinesdecidualizationembryoendometriumgynecological pathologiesimplantationmiRNANotchprimates

Identifiers

PMID32183093
PMCPMC7139778
OpenAlexW3011139590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.