Evidence map›Paper›PMID 32183076›Full record

ReviewMedical sciences (Basel, Switzerland)2020

Epidemiology of Bladder Cancer.

Kalyan Saginala, Adam Barsouk, John Sukumar Aluru, Prashanth Rawla, Sandeep Anand Padala, Alexander Barsouk

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Medical sciences (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 531 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
531citing papers in PubMed, 3 pooled it
95.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05783271 narecruitingnot on this mapstarted 2025, after this paper: background citation

Validity of Parametric MRI Using VIRAD Scoring in the Diagnosis of Cancer Bladder

TypeinterventionalSponsorAssiut UniversityRan2025 to 2026Enrolled58ConditionsBladder CancerArmsGadolinium
NCT05882747 completednot on this map

The Results of Surgery for Renal Cell Carcinoma Metastases in the Pancreas

TypeobservationalSponsorRigshospitalet, DenmarkRan2011 to 2022Enrolled25ConditionsSurgery
NCT06002269 nacompletednot on this mapstarted 2024, after this paper: background citation

A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients: the BOOST Study

TypeinterventionalSponsorUniversity of UtahRan2024 to 2025Enrolled8ConditionsBladder Cancer, Cystectomy, ChemotherapyArmsDietary and Exercise Intervention
3 · Its place in the literature

Who cites it

531 citing papers in PubMed, 3 syntheses or guidelines pooled it, 811 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Occupational benzene exposure and risk of kidney and bladder cancers: a systematic review and meta-analysis.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025
    Pooled it
  4. Trial
  5. Erdafitinib or Erdafitinib Plus Cetrelimab for Patients With Metastatic Urothelial Carcinoma andJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2026
    Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

471 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Kalyan SaginalaPlains Regional Medical Group Internal Medicine, Clovis, NM 88101, USA.
Adam BarsoukHillman Cancer Center, University of Pittsburgh, PA 15232, USA.
John Sukumar AluruSenior Research Associate, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02212, USA.
Prashanth RawlaDepartment of Medicine, Sovah Health, Martinsville, VA 24112, USA.
Sandeep Anand PadalaDepartment of Medicine, Nephrology, Augusta University, Medical College of Georgia, Augusta, GA 30912, USA.
Alexander BarsoukHematologist-Oncologist, Allegheny Health Network, Pittsburgh, PA 15212, USA.
UPMC Hillman Cancer Center · USAugusta University · USBeth Israel Deaconess Medical Center · USSovah Health Martinsville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on the latest GLOBOCAN data, bladder cancer accounts for 3% of global cancer diagnoses and is especially prevalent in the developed world. In the United States, bladder cancer is the sixth most incident neoplasm. A total of 90% of bladder cancer diagnoses are made in those 55 years of age and older, and the disease is four times more common in men than women. While the average 5-year survival in the US is 77%, the 5-year survival for those with metastatic disease is a measly 5%. The strongest risk factor for bladder cancer is tobacco smoking, which accounts for 50-65% of all cases. Occupational or environmental toxins likewise greatly contribute to disease burden (accounting for an estimated 20% of all cases), though the precise proportion can be obscured by the fact bladder cancer develops decades after exposure, even if the exposure only lasted several years. Schistosomiasis infection is the common cause of bladder cancer in regions of Africa and the Middle East and is considered the second most onerous tropical pathogen after malaria. With 81% of cases attributable to known risk factors (and only 7% to heritable mutations), bladder cancer is a prime candidate for prevention strategies. Smoking cessation, workplace safety practices, weight loss, exercise and schistosomiasis prevention (via water disinfection and mass drug administration) have all been shown to significantly decrease the risk of bladder cancer, which poses a growing burden around the world.

Indexed as

bladder cancerepidemiologyincidencemortalityprevalencepreventionrisk factors

Identifiers

PMID32183076
PMCPMC7151633
OpenAlexW3011714452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.