Evidence map›Paper›PMID 32182981›Full record

Trial reportNutrients2020

Early Morning Food Intake as a Risk Factor for Metabolic Dysregulation.

Ellen R Stothard, Hannah K Ritchie, Brian R Birks, Robert H Eckel, Janine Higgins, Edward L Melanson, Kenneth P Wright, Andrew W McHill

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. The role of circadian rhythm in osteoporosis; a review.Frontiers in cell and developmental biology · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Ellen R StothardSleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, 3100 Marine Street, Boulder, CO 80309, USA.
Hannah K RitchieSleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, 3100 Marine Street, Boulder, CO 80309, USA.
Brian R BirksSleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, 3100 Marine Street, Boulder, CO 80309, USA.
Robert H EckelDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, 12801 East 17th Avenue, Aurora, CO 80045, USA.
Janine HigginsDepartment of Pediatrics, Children's Hospital Colorado Anschutz Medical Campus, 13123 East 16th Ave, Aurora, CO 80045, USA.
Edward L MelansonDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, 12801 East 17th Avenue, Aurora, CO 80045, USA.
Kenneth P WrightSleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, 3100 Marine Street, Boulder, CO 80309, USA.
Andrew W McHillSleep and Chronobiology Laboratory, Department of Integrative Physiology, University of Colorado Boulder, 3100 Marine Street, Boulder, CO 80309, USA.ORCID 0000-0002-9428-6884
University of Colorado Boulder · USChildren's Hospital Colorado · USGeriatric Research Education and Clinical Center · USOregon Health & Science University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Circadian Misalignment and Energy MetabolismR21DK092624 · NIDDK · UNIVERSITY OF COLORADO · PI WRIGHT, KENNETH P · 2012 to 2013
$405k
Geriatric Research, Education, and the Clinical Center at the Denver VA Medical Center NANIDDK NIH HHS DK092624NIDDK NIH HHS P30 DK048520University of Colorado Boulder Dean's Graduate Student Research Grant NA
6 · The paper itself

Abstract

Increased risk of obesity and diabetes in shift workers may be related to food intake at adverse circadian times. Early morning shiftwork represents the largest proportion of shift workers in the United States, yet little is known about the impact of food intake in the early morning on metabolism. Eighteen participants (9 female) completed a counterbalanced 16 day design with two conditions separated by ~1 week: 8 h sleep opportunity at habitual time and simulated early morning shiftwork with 6.5 h sleep opportunity starting ~1 h earlier than habitual time. After wake time, resting energy expenditure (REE) was measured and blood was sampled for melatonin and fasting glucose and insulin. Following breakfast, post-prandial blood samples were collected every 40 min for 2 h and the thermic effect of food (TEF) was assessed for 3.25 h. Total sleep time was decreased by ~85 min (

Indexed as

AdultBlood GlucoseCircadian RhythmEatingEnergy IntakeEnergy MetabolismFastingFemaleHumansInsulinMaleMelatoninPolysomnographyPostprandial PeriodRisk FactorsSleepBlood GlucoseInsulinMelatonincircadianglucose toleranceshiftworksleep

Identifiers

PMID32182981
PMCPMC7146191
OpenAlexW3012182772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.