ArticleMolecules (Basel, Switzerland)2020
Induction of Apoptosis by Gluconasturtiin-Isothiocyanate (GNST-ITC) in Human Hepatocarcinoma HepG2 Cells and Human Breast Adenocarcinoma MCF-7 Cells.
Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
- Isothiocyanates as Multi-Target Natural Compounds in Leukemia: Mechanisms, Selectivity, and Therapeutic Potential.International journal of molecular sciences · 2026Review
- Isolation, Identification, and Antitumor Activities of Glucosinolates and Isothiocyanates in Chinese Cabbage Seeds.Foods (Basel, Switzerland) · 2025Article
- Watercress (Life (Basel, Switzerland) · 2025Review
- Effect of sodium selenite on the synthesis of glucosinolates and antioxidant capacity in Chinese cabbage (Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Quantification and Diversity Analyses of Major Glucosinolates in Conserved Chinese Cabbage (Foods (Basel, Switzerland) · 2023Article
- Moringa oleifera leaf extract induces osteogenic-like differentiation of human osteosarcoma SaOS2 cells.Journal of traditional and complementary medicine · 2022Article
- Microbial transglutaminase nanoflowers as an alternative nanomedicine for breast cancer theranostics.RSC advances · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
Abstract
Gluconasturtiin, a glucosinolate present in watercress, is hydrolysed by myrosinase to form gluconasturtiin-isothiocyanate (GNST-ITC), which has potential chemopreventive effects; however, the underlying mechanisms of action have not been explored, mainly in human cell lines. The purpose of the study is to evaluate the cytotoxicity of GNST-ITC and to further assess its potential to induce apoptosis. GNST-ITC inhibited cell proliferation in both human hepatocarcinoma (HepG2) and human breast adenocarcinoma (MCF-7) cells with IC
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Registered trials
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