Evidence map›Paper›PMID 32182954›Full record

ArticleCancers2020

In Vivo and In Vitro Anticancer Activity of Doxorubicin-loaded DNA-AuNP Nanocarrier for the Ovarian Cancer Treatment.

Chang-Seuk Lee, Tae Wan Kim, Da Eun Oh, Su Ok Bae, Jaesung Ryu, Hyejeong Kong, Hyeji Jeon, Hee Kyung Seo, Seob Jeon, Tae Hyun Kim

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Current Advances in Nanocarriers for Cancer Therapy.International journal of nanomedicine · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. A Journey to Reach the Ovary Using Next-Generation Technologies.International journal of molecular sciences · 2023
    Review
  10. Article
  11. The Proteolytic Landscape of Ovarian Cancer: Applications in Nanomedicine.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Article
  14. Article
  15. PrPInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chang-Seuk LeeDepartment of Chemistry, Soonchunhyang University, Asan 31538, Korea.
Tae Wan KimDepartment of Medical Life Science, Soonchunhyang University, Asan 31538, Korea.
Da Eun OhDepartment of Chemistry, Soonchunhyang University, Asan 31538, Korea.
Su Ok BaeDepartment of Chemistry, Soonchunhyang University, Asan 31538, Korea.
Jaesung RyuDepartment of Medical Life Science, Soonchunhyang University, Asan 31538, Korea.
Hyejeong KongDepartment of Medical Life Science, Soonchunhyang University, Asan 31538, Korea.
Hyeji JeonDepartment of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Korea.
Hee Kyung SeoDepartment of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Korea.
Seob JeonDepartment of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan 31151, Korea.
Tae Hyun KimDepartment of Chemistry, Soonchunhyang University, Asan 31538, Korea.
Soonchunhyang University · KR

Funding

Korea Environmental Industry and Technology Institute 2019002800001Soonchunhyang University 000000000
6 · The paper itself

Abstract

In this study, we have determined the anticancer activity of doxorubicin (Dox)-loaded DNA/gold nanoparticle (AuNP) nanocarrier (Dox-DNA-AuNP) for the treatment of ovarian cancer. The anticancer effect of Dox-DNA-AuNP was evaluated in vitro using the EZ-Cytox cell viability assay on three human ovarian cancer cell lines, SK-OV-3, HEY A8, and A2780. Dox-DNA-AuNP exhibited outstanding activity with good IC

Indexed as

doxorubicindrug deliverygold nanoparticlesNanomedicineovarian cancer

Identifiers

PMID32182954
PMCPMC7139456
OpenAlexW3010160178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.