Evidence map›Paper›PMID 32182934›Full record

ArticleInternational journal of molecular sciences2020

Acute and Chronic Nicotine Exposures Differentially Affect Central Serotonin 2A Receptor Function: Focus on the Lateral Habenula.

Cristiano Bombardi, Francis Delicata, Claudio Tagliavia, Massimo Pierucci, Gabriele Deidda, Maurizio Casarrubea, Philippe De Deurwaerdère, Giuseppe Di Giovanni

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Pathophysiology of the Serotonin System in the Nervous System and Beyond.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Lateral Habenula 5-HTInternational journal of molecular sciences · 2021
    Article
  9. Serotonin in Health and Disease.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Cristiano BombardiDipartimento di Scienze Mediche Veterinarie, Università di Bologna, Bologna, Via Tolara di Sopra, 50, 40064 Ozzano dell'Emilia (BO), Italy.ORCID 0000-0002-5685-1977
Francis DelicataDepartment of Physiology and Biochemistry, Laboratory of Neurophysiology, Faculty of Medicine and Surgery, University of Malta, MSD2080 Msida, Malta.ORCID 0000-0002-5339-5275
Claudio TagliaviaDipartimento di Scienze Mediche Veterinarie, Università di Bologna, Bologna, Via Tolara di Sopra, 50, 40064 Ozzano dell'Emilia (BO), Italy.
Massimo PierucciDepartment of Physiology and Biochemistry, Laboratory of Neurophysiology, Faculty of Medicine and Surgery, University of Malta, MSD2080 Msida, Malta.
Gabriele DeiddaDepartment of Physiology and Biochemistry, Laboratory of Neurophysiology, Faculty of Medicine and Surgery, University of Malta, MSD2080 Msida, Malta.
Maurizio CasarrubeaDepartment of Biomedicine, Neuroscience and Advances Diagnosis (BIND), Human Physiology Section "Giuseppe Pagano", Laboratory of Behavioral Physiology, University of Palermo, Viale delle Scienze n. 13, 90128 Palermo, Italy.ORCID 0000-0002-3278-6621
Philippe De DeurwaerdèreCentre National de la Recherche Scientifique (Unité Mixte de Recherche 5287), 146 rue Léo Saignat, B.P.281, F-33000 Bordeaux Cedex, France.
Giuseppe Di GiovanniDepartment of Physiology and Biochemistry, Laboratory of Neurophysiology, Faculty of Medicine and Surgery, University of Malta, MSD2080 Msida, Malta.ORCID 0000-0003-2006-563X
University of Malta · MTUniversity of Bologna · ITCentre National de la Recherche Scientifique · FRUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotine addiction is a serious public health problem causing millions of deaths worldwide. Serotonin (5-hydroxytryptamine; 5-HT) is involved in central nervous system (CNS) nicotine effects, and it has been suggested as a promising pharmacological target for smoking cessation. In this regard, what is particularly interesting are the 5-HT

Indexed as

AnimalsHabenulaMaleNeuronsNicotineRatsRats, Sprague-DawleyReceptor, Serotonin, 5-HT2ASerotoninNicotineReceptor, Serotonin, 5-HT2ASerotonin5-HT2CRaddictiondentate gyrusdepressiondorsal raphe nucleusmedial prefrontal cortexnucleus accumbensstriatumsubstantia nigra pars compactaventral tegmental area

Identifiers

PMID32182934
PMCPMC7084359
OpenAlexW3009138718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.