Evidence map›Paper›PMID 32182933›Full record

ArticleInternational journal of molecular sciences2020

Silver Nanoparticles in Zebrafish (

Liyuan Qiang, Zeinab H Arabeyyat, Qi Xin, Vesselin N Paunov, Imogen J F Dale, Richard I Lloyd Mills, Jeanette M Rotchell, Jinping Cheng

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Silver Nanoparticle-Induced Nephrotoxicity in Zebrafish (International journal of molecular sciences · 2025
    Article
  6. Review
  7. Synthesis of immunomodulatory biomimetic lipid polymer hybrid nanoparticles and application of zebrafish larvae in immunomodulation screening.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Changes of Gene Expression Patterns from Aquatic Organisms Exposed to Metal Nanoparticles.International journal of environmental research and public health · 2021
    Review
  20. Toxicological Profile of Plasmonic Nanoparticles in Zebrafish Model.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Liyuan QiangState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China.
Zeinab H ArabeyyatDepartment of Marine Biology, the University of Jordan, Aqaba branch, Aqaba 77111, Jordan.
Qi XinState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China.
Vesselin N PaunovDepartment of Chemistry and Biochemistry, University of Hull, Cottingham Road, Hull HU6 7RX, UK.ORCID 0000-0001-6878-1681
Imogen J F DaleSchool of Biological, Biomedical, and Environmental Sciences, University of Hull, Cottingham Road, Hull HU6 7RX, UK.
Richard I Lloyd MillsSchool of Biological, Biomedical, and Environmental Sciences, University of Hull, Cottingham Road, Hull HU6 7RX, UK.
Jeanette M RotchellSchool of Biological, Biomedical, and Environmental Sciences, University of Hull, Cottingham Road, Hull HU6 7RX, UK.
Jinping ChengState Key Laboratory of Estuarine and Coastal Research, East China Normal University, Shanghai 200062, China.

Funding

Natural Science Foundation of China 41101489the New Century Excellent Talents in University from Ministry of Education, China NECT-12-0181
6 · The paper itself

Abstract

Silver nanoparticles (AgNPs) are widely used in commercial applications as antimicrobial agents, but there have recently been increasing concerns raised about their possible environmental and health impacts. In this study, zebrafish embryos were exposed to two sizes of AgNP, 4 and 10 nm, through a continuous exposure from 4 to 96 h post-fertilisation (hpf), to study their uptake, impact and molecular defense responses. Results showed that zebrafish embryos were significantly impacted by 72 hpf when continuously exposed to 4 nm AgNPs. At concentrations above 0.963 mg/L, significant in vivo uptake and delayed yolk sac absorption was evident; at 1.925 mg/L, significantly reduced body length was recorded compared to control embryos. Additionally, 4 nm AgNP treatment at the same concentration resulted in significantly upregulated

Indexed as

AnimalsEmbryonic DevelopmentEmbryo, NonmammalianLarvaMetal NanoparticlesParticle SizeRNA, MessengerSilverTranscription, GeneticWater Pollutants, ChemicalZebrafishRNA, MessengerSilverWater Pollutants, Chemicalcontinuous exposuredevelopmental toxicityembryos (D. rerio)molecular responsesilver nanoparticlesuptake

Identifiers

PMID32182933
PMCPMC7084859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.