ArticleSensors (Basel, Switzerland)2020
A Lamping U-Shaped Fiber Biosensor Detector for MicroRNA.
Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Overview of Optical Fiber Biosensors for the Detection of Cancer Biomarkers in the Past Decade.ACS omega · 2026Review
- The silent dialogue between cells: regulatory roles of non-coding RNAs in cardiovascular disease.Frontiers in cell and developmental biology · 2026Review
- Recent Advances in Biosensor Technology for Early-Stage Detection of Hepatocellular Carcinoma-Specific Biomarkers: An Overview.Diagnostics (Basel, Switzerland) · 2024Review
- Portable optical fiber biosensors integrated with smartphone: technologies, applications, and challenges [Invited].Biomedical optics express · 2024Review
- Article
- Long-Period Fiber Grating Sensors for Chemical and Biomedical Applications.Sensors (Basel, Switzerland) · 2023Review
- Novel Optical Fiber-Based Structures for Plasmonics Sensors.Biosensors · 2022Review
- An Interplay between Lossy Mode Resonance and Surface Plasmon Resonance and Their Sensing Applications.Biosensors · 2022Article
- SARS-CoV-2 spike protein detection using slightly tapered no-core fiber-based optical transducer.Mikrochimica acta · 2022Article
- Cost-Effective Fiber Optic Solutions for Biosensing.Biosensors · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
This study presents a U-shaped optical fiber developed for a facile application of microRNA detection. It is fabricated by the lamping process and packaged in a quartz tube to eliminate human negligence. In addition, silanization and electrostatic self-assembly are employed to bind gold nanoparticles and miRNA-133a probe onto the silicon dioxide of the fiber surface. For Mahlavu of hepatocellular carcinoma (HCC), detection is determined by the wavelength shift and transmission loss of a U-shaped optical fiber biosensor. The spectral sensitivity of wavelength and their coefficient of determination are found at -218.319 nm/ ng/mL and 0.839, respectively. Concurrently, the sensitivity of transmission loss and their coefficient of determination are found at 162.394 dB/ ng/mL and 0.984, respectively. A method for estimating the limit of detection of Mahlavu is at 0.0133 ng/mL. The results show that the proposed U-shaped biosensor is highly specific to miRNA-133a and possesses good sensitivity to variations in specimen concentration. As such, it could be of substantial value in microRNA detection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.