Evidence map›Paper›PMID 32182864›Full record

ArticleGenes2020

Transcriptomic Profiling of DAF-7/TGFβ Pathway Mutants in

Muhan Hu, David Crossman, Jeevan K Prasain, Michael A Miller, Rosa A Serra

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. The AMPylase FIC-1 modulates TGF-β signaling inFrontiers in molecular neuroscience · 2022
    Article
  6. Review
  7. Mechanisms of TGFß in prostaglandin synthesis and sperm guidance in Caenorhabditis elegans.Developmental dynamics : an official publication of the American Association of Anatomists · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Muhan HuDepartment of Cell Development and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
David CrossmanDepartment of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jeevan K PrasainDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Michael A MillerDepartment of Cell Development and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Rosa A SerraDepartment of Cell Development and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
University of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI OLAF KUTSCH · 1988 to 2026
$84.1M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Genetic Regulation of Unconventional Prostaglandin MetabolismR01GM118361 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PRASAIN, JEEVAN KUMAR, YODER, BRADLEY K. · 2016 to 2019
$1.2M
Mechanisms of TGFb in prostaglandin metabolism and fertilizationF30HD094446 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HU, MUHAN · 2018 to 2021
$132k
NCI NIH HHS P30 CA013148NIAID NIH HHS P30 AI027767NICHD NIH HHS F30 HD094446NIGMS NIH HHS R01 GM118361NIH HHS P40 OD010440
6 · The paper itself

Abstract

The transforming growth factor beta superfamily encompasses a large family of ligands that are well conserved across many organisms. They are regulators of a number of physiological and pathological processes. The model nematode

Indexed as

TranscriptomeAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsMutationReceptors, Cell SurfaceSignal TransductionSmad ProteinsTransforming Growth Factor betaCaenorhabditis elegans ProteinsDAF-1 protein, C elegansDAF-3 protein, C elegansDAF-7 protein, C elegansReceptors, Cell SurfaceSmad ProteinsTransforming Growth Factor betaC. elegansdaf-1daf-3gene ontologyqPCRRNA sequencingTGFβ

Identifiers

PMID32182864
PMCPMC7140792
OpenAlexW3009230164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.