ArticlePloS one2020
Risk factors of the progression to hypertension and characteristics of natural history during progression: A national cohort study.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Church-Sponsored Promotornan di Salú/Community Health Worker-Led Health Fair Promoting Hypertension Awareness in Willemstad, Curaçao: A Pilot Study Assessing Participant Satisfaction and Experience.International journal of environmental research and public health · 2025Article
- Hypertension Remission After Bariatric Surgery: Metrics, Mechanisms, and Patient Selection.Current cardiology reports · 2025Review
- Arterial stiffness and biochemical profiles in prehypertensive, normotensive, and controlled hypertensive individuals: a cross-sectional study.Frontiers in cardiovascular medicine · 2025Article
- Comparison of seven anthropometric indexes to predict hypertension plus hyperuricemia among U.S. adults.Frontiers in endocrinology · 2024Article
- Predicting the risk of hypertension using machine learning algorithms: A cross sectional study in Ethiopia.PloS one · 2023Article
- Trends and influence factors in the prevalence, awareness, treatment, and control of hypertension among US adults from 1999 to 2018.PloS one · 2023Article
- A longitudinal analysis of the progression from normal blood pressure to stage 2 hypertension: A 12-year Korean cohort.BMC public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the high disease burden that results from cardiovascular complications of hypertension, factors related to the progression to hypertension in the normotensive population are not actively reported. The purpose of this study was to estimate the rate of the progression to hypertension and to reveal the associated risk factors.
methodsThe study included normotensive participants from the National Health Insurance Service-National Health Screening Cohort, and contained a 10% sample of all adults who received a national health screening test in either 2002 or 2003. At the end of the study in 2015, the patients were divided into two groups based on whether or not they progressed to hypertension. Cox proportional hazard modeling was performed to identify risk factors for progression. Subgroup analysis using logistic regression was employed to reveal factors influencing the different natural history of the progression.
resultsAmong the 75,335 included participants, the progression rate to hypertension was 66.39% (50,013), with an adjusted incidence rate of 8.62 per 100 person-year in the aged 40-64 group and 12.68 in the aged 65 or above group. Age, BMI, hemoglobin, and family history of hypertension and other diseases were related to the progression. Among the progression group, 78.21% (39,116) participants skipped a pre-hypertensive status; this group consisted of older females with lower pulse pressure and more alcohol consumption compared to people who had pre-hypertensive status before the progression.
conclusionSubstantial risk factors for the progression to hypertension should be carefully managed even in normotensive participants who receive health screening tests.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.