Evidence map›Paper›PMID 32182119›Full record

ArticleCancer biotherapy & radiopharmaceuticals2020

Preclinical Single Photon Emission Computed Tomography of Alpha Particle-Emitting Radium-223.

Diane S Abou, Andrew Rittenbach, Ryan E Tomlinson, Paige A Finley, Benjamin Tsui, Brian W Simons, Abhinav K Jha, David Ulmert, Ryan C Riddle, Daniel L J Thorek

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer biotherapy & radiopharmaceuticals, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. A Projection-Domain Low-Count Quantitative SPECT Method forIEEE transactions on radiation and plasma medical sciences · 2023
    Article
  5. Why bother with alpha particles?European journal of nuclear medicine and molecular imaging · 2021
    Article
  6. Prostate Cancer Theranostics - An Overview.Frontiers in oncology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Diane S AbouDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Andrew RittenbachInformation Sciences Institute, University of Southern California, Los Angeles, California, USA.
Ryan E TomlinsonDepartment of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Paige A FinleyDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Benjamin TsuiDepartment of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Brian W SimonsCenter for Comparative Medicine, Baylor College of Medicine, Houston, Texas, USA.
Abhinav K JhaDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
David UlmertDepartment of Molecular and Medical Pharmacology, University of California Los Angeles, Los Angeles, California, USA.
Ryan C RiddleDepartment of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Daniel L J ThorekDepartment of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Johns Hopkins University · USWashington University in St. Louis · USBaylor College of Medicine · USThomas Jefferson University · USUniversity of California, Los Angeles · USUniversity of Southern California · US

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
TRANSGENIC MODELS FOR PROSTATE CANCER AND AUTOIMMUNITYP50CA058236 · NCI · JOHNS HOPKINS UNIVERSITY · PI DENMEADE, SAMUEL R · 1992 to 2020
$43.9M
The Radium-223 Combination Therapy Space; Improving Response and Clarifying ToxicitiesR01CA240711 · NCI · WASHINGTON UNIVERSITY · PI MICHALSKI, JEFF M., THOREK, DANIEL LYNDON JAFFE · 2020 to 2024
$2.2M
Opening the Therapeutic Window for PSMA-Targeted Molecular RadiotherapyR01CA229893 · NCI · WASHINGTON UNIVERSITY · PI THOREK, DANIEL LYNDON JAFFE · 2019 to 2024
$1.9M
Kallikrein-Targeted Alpha-Particle Therapy of Late-Stage Prostate CancerR01CA201035 · NCI · WASHINGTON UNIVERSITY · PI THOREK, DANIEL LYNDON JAFFE · 2017 to 2020
$1.4M
NCI NIH HHS P30 CA016042NCI NIH HHS P50 CA058236NCI NIH HHS R01 CA201035NCI NIH HHS R01 CA229893NCI NIH HHS R01 CA240711
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAutoradiographyBone and BonesBone NeoplasmsHumansMaleMiceModels, AnimalPhantoms, ImagingProstatic Neoplasms, Castration-ResistantRadioisotopesRadiopharmaceuticalsRadiumTissue DistributionTomography, Emission-Computed, Single-PhotonRadioisotopesRadiopharmaceuticalsRadiumradium Ra 223 dichloridemolecular imagingpharmacokineticstheranosticsα-particle radiotherapy

Identifiers

PMID32182119
PMCPMC7475100
OpenAlexW3011215228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.