Evidence map›Paper›PMID 32182034›Full record

ArticleACS chemical biology2020

Designer Palmitoylation Motif-Based Self-Localizing Ligand for Sustained Control of Protein Localization in Living Cells and

Akinobu Nakamura, Choji Oki, Shunsuke Sawada, Tatsuyuki Yoshii, Keiko Kuwata, Andrew K Rudd, Neal K Devaraj, Kentaro Noma, Shinya Tsukiji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Induced proximity-based therapeutic modalities.Nature reviews. Drug discovery · 2026
    Review
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Akinobu NakamuraDepartment of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.
Choji OkiDepartment of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.
Shunsuke SawadaDepartment of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.
Tatsuyuki YoshiiDepartment of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.ORCID 0000-0002-3465-4219
Keiko KuwataInstitute of Transformative Bio-Molecules (ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.
Andrew K RuddDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.
Neal K DevarajDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California 92093, United States.ORCID 0000-0002-8033-9973
Kentaro NomaPRESTO, Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.
Shinya TsukijiDepartment of Life Science and Applied Chemistry, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.ORCID 0000-0002-1402-5773

Funding

Amplifying PET Imaging Signals for In Vivo Detection of Pancreatic Beta-cellsDP2DK111801 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEVARAJ, NEAL KRISHNA · 2016 to 2018
$2.0M
NIDDK NIH HHS DP2 DK111801
6 · The paper itself

Abstract

Inducing protein translocation to the plasma membrane (PM) is an important approach for manipulating diverse signaling molecules/pathways in living cells. We previously devised a new chemogenetic system, in which a protein fused to

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Line, TumorCell MembraneCysteineEscherichia coliEscherichia coli ProteinsGolgi ApparatusHumansLigandsLipoylationProtein TransportProto-Oncogene Proteins c-rafRatsRecombinant Fusion ProteinsCaenorhabditis elegans ProteinsCysteineEscherichia coli ProteinsLigandsProto-Oncogene Proteins c-rafRecombinant Fusion ProteinsTetrahydrofolate DehydrogenaseTrimethoprim

Identifiers

PMID32182034
PMCPMC8849012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.