Evidence map›Paper›PMID 32181505›Full record

ArticleThe British journal of surgery2020

Core outcome set for uncomplicated acute appendicitis in children and young people.

F C Sherratt, B S R Allin, J J Kirkham, E Walker, B Young, W Wood, L Beasant, Appendicitis Core Outcome Set Study Group, S Eaton, N J Hall

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

F C SherrattInstitute of Population Health Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0003-4147-9305
B S R AllinNational Perinatal Epidemiology Unit, University of Oxford, Oxford, UK.
J J KirkhamCentre for Biostatistics, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
E WalkerCentre for Outcomes and Experience Research in Children's Health Illness and Disability (ORCHID), Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
B YoungInstitute of Population Health Sciences, University of Liverpool, Liverpool, UK.
W WoodNational Institute for Health Research (NIHR) Research Design Service South Central, University of Southampton, Southampton, UK.
L BeasantBristol Medical School, University of Bristol, Bristol, UK.
Appendicitis Core Outcome Set Study Group
S EatonDevelopmental Biology and Cancer Programme, University College London Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0003-0892-9204
N J HallUniversity Surgery Unit, Faculty of Medicine, University of Southampton, Southampton, UK.ORCID 0000-0001-8570-9374

Funding

Department of Health 14/192/90Health Technology Assessment Programme 14/192/90Medical Research Council MR/K025643/1
6 · The paper itself

Abstract

backgroundResearch studies to inform clinical practice and policy in children and young people with appendicitis are hampered by inconsistent selection and reporting of outcomes. The aim of this study was to develop a core outcome set for reporting all studies of uncomplicated acute appendicitis in children and young people.

methodsSystematic literature reviews, qualitative interviews with parents and patients treated for uncomplicated acute appendicitis, and a Study-Specific Advisory Group informed a long list of outcomes. Outcomes were then prioritized by stakeholders based in the UK (patients, parents, and paediatric and general surgeons) in an online three-round Delphi consensus process, followed by face-to-face consensus meetings.

resultsA long list of 40 items was scored by 147 key stakeholders in the first Delphi round, of whom 90 completed the two subsequent Delphi rounds. The final core outcome set comprises 14 outcomes: intra-abdominal abscess, reoperation (including interventional radiology procedure), readmission to hospital, bowel obstruction, wound infection, antibiotic failure, wound complication, negative appendicectomy, recurrent appendicitis, death, patient stress/psychological distress, length of hospital stay, time away from full activity and child's quality of life.

conclusionA core outcome set comprising 14 outcomes across five key domains has been developed for reporting studies in children and young people with uncomplicated acute appendicitis. Further work is required to determine how and when to measure these outcomes.

Indexed as

Acute DiseaseAdolescentAppendectomyAppendicitisChildChild, PreschoolConsensusDelphi TechniqueHumansLength of StayOutcome Assessment, Health CarePostoperative ComplicationsRecurrence

Identifiers

PMID32181505
PMCPMC7317752

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.