Evidence map›Paper›PMID 32181346›Full record

ArticleScience advances2020

Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells.

Helena G Asenjo, Amador Gallardo, Lourdes López-Onieva, Irene Tejada, Jordi Martorell-Marugán, Pedro Carmona-Sáez, David Landeira

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  5. Polycomb function in early mouse development.Cell death and differentiation · 2025
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  19. Maintaining Transcriptional Specificity Through Mitosis.Annual review of genomics and human genetics · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Helena G AsenjoCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0003-1904-1606
Amador GallardoCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.
Lourdes López-OnievaCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.
Irene TejadaCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.
Jordi Martorell-MarugánCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0002-5186-0735
Pedro Carmona-SáezCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0002-6173-7255
David LandeiraCentre for Genomics and Oncological Research (GENYO), Avenue de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0002-3267-454X
Universidad de Granada · ESPfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When self-renewing pluripotent cells receive a differentiation signal, ongoing cell duplication needs to be coordinated with entry into a differentiation program. Accordingly, transcriptional activation of lineage specifier genes and cell differentiation is confined to the G

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsCell CycleCell DifferentiationCell Line, TransformedChromatinElonginEnhancer of Zeste Homolog 2 ProteinMiceMice, Inbred C57BLMice, KnockoutMouse Embryonic Stem CellsPolycomb Repressive Complex 2Promoter Regions, GeneticProtein BindingProtein SubunitsChromatinElob protein, mouseElonginEnhancer of Zeste Homolog 2 ProteinEzh2 protein, mouseJarid2 protein, mousePolycomb Repressive Complex 2Protein SubunitsRNA Polymerase II

Identifiers

PMID32181346
PMCPMC7056320
OpenAlexW3009676306

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.