Evidence map›Paper›PMID 32181314›Full record

ArticlePractical laboratory medicine2020

Rapid

M Rabie Al-Turkmani, Michael A Suriawinata, Sophie J Deharvengt, Donald C Green, Candice C Black, Keisuke Shirai, Konstantin H Dragnev, Gregory J Tsongalis

Open access · goldAbstract read
In one paragraph

Article in Practical laboratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Contribution of the IdyllaCurrent oncology (Toronto, Ont.) · 2021
    Article
  3. Article
  4. Testing EGFR with Idylla on Cytological Specimens of Lung Cancer: A Review.International journal of molecular sciences · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

M Rabie Al-TurkmaniDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Michael A SuriawinataDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Sophie J DeharvengtDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Donald C GreenDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Candice C BlackDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Keisuke ShiraiDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Konstantin H DragnevDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Gregory J TsongalisDartmouth-Hitchcock Medical Center and Geisel School of Medicine at Dartmouth. Lebanon, NH, USA.
Dartmouth–Hitchcock Medical Center · US

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
NCI NIH HHS P30 CA023108
6 · The paper itself

Abstract

introductionActivating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (

methodsThirty-four FFPE lung adenocarcinoma tissue samples were tested on the Idylla™ system. 21 had at least one mutation in

resultsIdylla™ results were in complete agreement with those obtained by NGS for

conclusionThe fully automated Idylla™ system offers rapid and reliable testing for clinically actionable mutations in

Identifiers

PMID32181314
PMCPMC7062922
OpenAlexW3009738014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.