Evidence map›Paper›PMID 32181255›Full record

ArticleFrontiers in medicine2020

Use of Eltrombopag in Children With Chronic Immune Thrombocytopenia (ITP): A Real Life Retrospective Multicenter Experience of the Italian Association of Pediatric Hematology and Oncology (AIEOP).

Paola Giordano, Giuseppe Lassandro, Angelica Barone, Simone Cesaro, Ilaria Fotzi, Fiorina Giona, Saverio Ladogana, Maurizio Miano, Antonio Marzollo, Margherita Nardi and 10 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06568913 (The Outcome of the Thrombopoietin Receptor Agonists in Pediatric Patient With Persistent or Chronic ITP Unresonsive to Steroids), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06568913 narecruitingnot on this mapstarted 2024, after this paper: background citation

The Outcome of the Thrombopoietin Receptor Agonists in Pediatric Patient With Persistent or Chronic ITP Unresonsive to Steroids

TypeinterventionalSponsorSohag UniversityRan2024 to 2025Enrolled100ConditionsPersistent or Chronic ITP Not Respnding to SteroidsArmsCBC
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Eltrombopag Effectiveness and Tolerability in Chronic Immune Thrombocytopenia: A Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
  2. Safety and efficacy of eltrombopag in the treatment of children with immune thrombocytopenia: a Meta analysis.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 1 country.

Paola GiordanoPediatric Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
Giuseppe LassandroPediatric Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
Angelica BaroneDepartment of Pediatric Onco-Hematology, University Hospital of Parma, Parma, Italy.
Simone CesaroPediatric Hematology Oncology, Department of Mother and Child, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Ilaria FotziDepartment Pediatric Hematology Oncology, Azienda Ospedaliero Universitaria A. Meyer Children Hospital, Florence, Italy.
Fiorina GionaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Saverio LadoganaDepartment of Hematology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
Maurizio MianoClinical and Experimental Hematology Unit, "G. Gaslini" Children's Hospital, Genoa, Italy.
Antonio MarzolloPediatric Hematology-Oncology Unit, Department of Women's and Children's Health, Azienda Ospedaliera-University of Padova, Padua, Italy.
Margherita NardiPediatric Hematology, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Lucia Dora NotarangeloHemato-Oncology Unit, Children Hospital, Spedali Civili, Brescia, Italy.
Andrea PessionDepartment of Pediatrics, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Antonio RuggieroPediatric Oncology Unit, Fondazione Policlinico Universitario Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Giovanna RussoPediatric Hemato-Oncology Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Paola SaraccoPediatric Hematology, Department of Pediatrics, University Hospital Città della Salute e della Scienza, Turin, Italy.
Marco SpinelliHemato-Oncology Unit, Fondazione MBBM, San Gerardo Hospital, Monza, Italy.
Alessandra TolvaPediatric Hematology/Oncology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.
Assunta TorneselloPediatric Hematology Oncology, Presidio Ospedaliero Vito Fazzi, Lecce, Italy.
Valentina PalladinoPediatric Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
Giovanni Carlo Del VecchioPediatric Unit, Department of Biomedical Science and Human Oncology, University of Bari "Aldo Moro", Bari, Italy.
University of Bari Aldo Moro · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera di Padova · ITAzienda Ospedaliera San Gerardo · ITAzienda Ospedaliera Universitaria Integrata Verona · ITAzienda Ospedaliera Universitaria Pisana · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITCasa Sollievo della Sofferenza · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Giannina Gaslini · ITMeyer Children's Hospital · ITOspedale Vito Fazzi · ITPoliclinico S.Orsola-Malpighi · ITSapienza University of Rome · ITUniversity of Catania · ITUniversity of Parma · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

bleeding disorderschildreneltrombopagimmune thrombocytopeniathrombopoietin receptor agonists

Identifiers

PMID32181255
PMCPMC7059456
OpenAlexW3008268408

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.