Evidence map›Paper›PMID 32181040›Full record

ArticleCase reports in pediatrics2020

Pediatric Collagenous Gastroenterocolitis Successfully Treated with Methotrexate.

Beate C Beinvogl, Jeffrey D Goldsmith, Ramalingam Arumugam, Michelle Kennedy, Mani Mokalla, Paul A Rufo, Menno Verhave

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Beate C BeinvoglDivision of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0001-9303-3474
Jeffrey D GoldsmithDepartment of Pathology, Boston Children's Hospital, Boston, MA, USA.
Ramalingam ArumugamMinnesota Gastroenterology, PA, St. Paul, MN, USA.
Michelle KennedyMinnesota Gastroenterology, PA, St. Paul, MN, USA.
Mani MokallaChildren's Hospitals and Clinics of Minnesota, Minneapolis, MN, USA.
Paul A RufoDivision of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-1719-4118
Menno VerhaveDivision of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.
Boston Children's Hospital · USMNGI Digestive Health · USChildren's Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A two-and-one-half-year-old previously healthy female presented with a ten-week history of watery diarrhea, nonbilious and nonbloody emesis, and low-grade fevers. She was found to have severe hypoalbuminemia and hypogammaglobulinemia. Her symptoms persisted, and she became dependent on parenteral nutrition. Biopsies obtained during subsequent endoscopic and colonoscopic studies revealed findings consistent with collagenous gastroenterocolitis. She responded to an empiric course of prednisone, but her symptoms recurred shortly after transitioning to oral budesonide. After successful reinduction with intravenous prednisone, intramuscular methotrexate was initiated. She remained asymptomatic during a 15-month course of therapy, and she continued to do well clinically until approximately nine months after weaning off methotrexate. At that point, she experienced a recurrence of diarrhea, and repeat endoscopic evaluation confirmed collagenous colitis. This responded nicely to a short course of oral budesonide, and she has since remained asymptomatic and off any therapy.

Identifiers

PMID32181040
PMCPMC7060430
OpenAlexW3007455177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.