Evidence map›Paper›PMID 32180772›Full record

ArticleFrontiers in immunology2020

The Immunomodulator 1-Methyltryptophan Drives Tryptophan Catabolism Toward the Kynurenic Acid Branch.

Elisa Wirthgen, Anne K Leonard, Christian Scharf, Grazyna Domanska

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Archives of Razi Institute · 2024
    Article
  8. iScience · 2023
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. The Function of the Kynurenine Pathway in the Placenta: A Novel Pharmacotherapeutic Target?International journal of environmental research and public health · 2021
    Review
  14. Tryptophan-derived serotonin-kynurenine balance in immune activation and intestinal inflammation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elisa WirthgenDepartment of Pediatrics, Rostock University Medical Center, Rostock, Germany.
Anne K LeonardInstitute of Biochemistry, University Medicine Greifswald, Greifswald, Germany.
Christian ScharfDepartment of Otorhinolaryngology, Head and Neck Surgery, University Medicine Greifswald, Greifswald, Germany.
Grazyna DomanskaInstitute of Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.
Universitätsmedizin Greifswald · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCells, CulturedHumansImmunologic FactorsIndoleamine-Pyrrole 2,3,-DioxygenaseKynurenic AcidMetabolismMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutTandem Mass SpectrometryTryptophan1-methyltryptophanIDO1 protein, mouseImmunologic FactorsIndoleamine-Pyrrole 2,3,-DioxygenaseKynurenic AcidTryptophan1-MTIDOKYNAkynurenine pathwaytryptophan

Identifiers

PMID32180772
PMCPMC7059861
OpenAlexW3007823211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.