Evidence map›Paper›PMID 32180707›Full record

ArticleFrontiers in cellular neuroscience2020

Slowing of the Time Course of Acidification Decreases the Acid-Sensing Ion Channel 1a Current Amplitude and Modulates Action Potential Firing in Neurons.

Omar Alijevic, Olivier Bignucolo, Echrak Hichri, Zhong Peng, Jan P Kucera, Stephan Kellenberger

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Photomodulation of the ASIC1a acidic pocket destabilizes the open state.Protein science : a publication of the Protein Society · 2023
    Article
  4. Possible Compensatory Role of ASICs in Glutamatergic Synapses.International journal of molecular sciences · 2023
    Article
  5. Article
  6. Postsynaptic Calcium Extrusion at the Mouse Neuromuscular Junction Alkalinizes the Synaptic Cleft.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Changes in HFrontiers in cellular neuroscience · 2021
    Article
  15. Review
  16. Signaling Pathways in Proton and Non-proton ASIC1a Activation.Frontiers in cellular neuroscience · 2021
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Omar AlijevicDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.
Olivier BignucoloDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.
Echrak HichriDepartment of Physiology, University of Bern, Bern, Switzerland.
Zhong PengDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.
Jan P KuceraDepartment of Physiology, University of Bern, Bern, Switzerland.
Stephan KellenbergerDepartment of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.
University of Lausanne · CHUniversity of Bern · CHSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acid-sensing ion channels (ASICs) are H

Indexed as

acidificationASICHodgkin-Huxley modelkinetic modelneuronal signalingpatch-clamp

Identifiers

PMID32180707
PMCPMC7059123
OpenAlexW3007862679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.