Evidence map›Paper›PMID 32180175›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2020

Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: a case series of 17 patients.

Rong Chen, Yuan Zhang, Lei Huang, Bi-Heng Cheng, Zhong-Yuan Xia, Qing-Tao Meng

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 24 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 24 pooled it
27.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 24 syntheses or guidelines pooled it, 294 citations in OpenAlex.

  1. Treatment of COVID-19 in pregnant women: A systematic review and meta-analysis.European journal of obstetrics, gynecology, and reproductive biology · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Clinical Presentation and Outcomes of Pregnant Women With Coronavirus Disease 2019: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Impact of COVID-19 on maternal and neonatal outcomes: a systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021
    Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Pooled it
  17. Pooled it
  18. COVID-19 and pregnancy: A review of clinical characteristics, obstetric outcomes and vertical transmission.The Australian & New Zealand journal of obstetrics & gynaecology · 2020
    Pooled it
  19. Pooled it
  20. Pooled it

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rong Chen *Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Yuan Zhang *Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Lei HuangDepartment of Anesthesiology, East Hospital, Renmin Hospital of Wuhan University, Wuhan, China.
Bi-Heng ChengDepartment of Obstetric, East Hospital, Renmin Hospital of Wuhan University, Wuhan, China.
Zhong-Yuan Xia *Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Qing-Tao Meng *Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China. mengqingtao2018@126.com.
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the management and safety of epidural or general anesthesia for Cesarean delivery in parturients with coronavirus disease (COVID-19) and their newborns, and to evaluate the standardized procedures for protecting medical staff.

methodsWe retrospectively reviewed the cases of parturients diagnosed with severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection disease (COVID-19). Their epidemiologic history, chest computed tomography scans, laboratory measurements, and SARS-CoV-2 nucleic acid positivity were evaluated. We also recorded the patients' demographic and clinical characteristics, anesthesia and surgery-related data, maternal and neonatal complications, as well as the health status of the involved medical staff.

resultsThe clinical characteristics of 17 pregnant women infected with SARS-CoV-2 were similar to those previously reported in non-pregnant adult patients. All of the 17 patients underwent Cesarean delivery with anesthesia performed according to standardized anesthesia/surgery procedures. Fourteen of the patients underwent continuous epidural anesthesia with 12 experiencing significant intraoperative hypotension. Three patients received general anesthesia with tracheal intubation because emergency surgery was needed. Three of the parturients are still recovering from their Cesarean delivery and are receiving in-hospital treatment for COVID-19. Three neonates were born prematurely. There were no deaths or serious neonatal asphyxia events. All neonatal SARS-CoV-2 nucleic acid tests were negative. No medical staff were infected throughout the patient care period.

conclusionsBoth epidural and general anesthesia were safely used for Cesarean delivery in the parturients with COVID-19. Nevertheless, the incidence of hypotension during epidural anesthesia appeared excessive. Proper patient transfer, medical staff access procedures, and effective biosafety precautions are important to protect medical staff from COVID-19.

Indexed as

Anesthesia, EpiduralAnesthesia, GeneralCesarean SectionCoronavirus InfectionsPandemicsPneumonia, ViralCOVID-19FemaleHumansInfant, NewbornInfection ControlInfectious Disease Transmission, Patient-to-ProfessionalPregnancyRetrospective StudiesTreatment Outcome

Identifiers

PMID32180175
PMCPMC7090434
OpenAlexW3011116377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.