ReviewAging clinical and experimental research2020
Using the Multidimensional Prognostic Index (MPI) to improve cost-effectiveness of interventions in multimorbid frail older persons: results and final recommendations from the MPI_AGE European Project.
Review in Aging clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 45 citations in OpenAlex.
- Trial
- The sound of longevity: music and technology for healthy ageing.Aging clinical and experimental research · 2026Review
- Comorbidity patterns and mortality in atrial fibrillation: a latent class analysis of the EURopean study of Older Subjects with Atrial Fibrillation (EUROSAF).Annals of medicine · 2025Article
- Exploring Frailty Status and Blood Biomarkers: A Multidimensional Approach to Alzheimer's Diagnosis.Geriatrics (Basel, Switzerland) · 2025Article
- Long-Term Outcome of Elderly Patients with Severe Aortic Stenosis Undergoing a Tailored Interventional Treatment Using Frailty-Based Management: Beyond the Five-Year Horizon.Journal of personalized medicine · 2024Article
- Technological monitoring of motor parameters to assess multidimensional frailty of older people in the PRO-HOME project.Scientific reports · 2024Article
- Management of Clostridioides difficile infection: an Italian Delphi consensus.The Journal of antimicrobial chemotherapy · 2024Article
- The Multidimensional Prognostic Index predicts incident delirium among hospitalized older patients with COVID-19: a multicenter prospective European study.European geriatric medicine · 2024Article
- A Comprehensive Geriatric Workup and Frailty Assessment in Older Patients with Severe Aortic Stenosis.Journal of clinical medicine · 2024Review
- Association of Vulnerability Screening on Hospital Admission with Discharge to Rehabilitation-Oriented Care after Acute Hospital Stay.Annals of geriatric medicine and research · 2023Article
- Frailty and anticoagulants in older subjects with atrial fibrillation: the EUROSAF study.Age and ageing · 2023Article
- Review
- Can the Multidimensional Prognostic Index (MPI) be a predictive instrument for mortality in older adult liver transplant candidates?European geriatric medicine · 2023Observational
- Biomarkers for risk stratification and antibiotic stewardship in elderly patients.Aging clinical and experimental research · 2023Review
- High Prevalence of Geriatric Conditions Among Older Adults With Cardiovascular Disease.Journal of the American Heart Association · 2023Review
- Older People Hospitalized for COVID-19: Prognostic Role of Multidimensional Prognostic Index and Other Prognostic Scores.Journal of clinical medicine · 2023Article
- Medium and long-term prognosis in hospitalised older adults with multimorbidity. A prospective cohort study.PloS one · 2023Article
- The role of prognostic stratification on prescription of anticoagulants in older patients with atrial fibrillation: a multicenter, observational, prospective European study (EUROSAF).Annals of medicine · 2022Observational
- Multidimensional frailty and quality of life: data from the English Longitudinal Study of Ageing.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- It Is Time for Senescience.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
12 authors at 9 institutions in 9 countries.
Funding
Abstract
MPI_AGE is a European Union co-funded research project aimed to use the Multidimensional Prognostic Index (MPI), a validated Comprehensive Geriatric Assessment (CGA)-based prognostic tool, to develop predictive rules that guide clinical and management decisions in older people in different European countries. A series of international studies performed in different settings have shown that the MPI is useful to predict mortality and risk of hospitalization in community-dwelling older subjects at population level. Furthermore, studies performed in older people who underwent a CGA before admission to a nursing home or receiving homecare services showed that the MPI successfully identified groups of persons who could benefit, in terms of reduced mortality, of specific therapies such as statins in diabetes mellitus and coronary artery disease, anticoagulants in atrial fibrillation and antidementia drugs in cognitive decline. A prospective trial carried out in nine hospitals in Europe and Australia demonstrated that the MPI was able to predict not only in-hospital and long-term mortality, but also institutionalization, re-hospitalization and receiving homecare services during the one-year follow-up after hospital discharge. The project also explored the association between MPI and mortality in hospitalized older patients in need of complex procedures such as transcatheter aortic valve implantation or enteral tube feeding. Evidence from these studies has prompted the MPI_AGE Investigators to formulate recommendations for healthcare providers, policy makers and the general population which may help to improve the cost-effectiveness of appropriate health care interventions for older patients.
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