SynthesisJournal of molecular neuroscience : MN2020
Association Between Stroke and Parkinson's Disease: a Meta-analysis.
Synthesis in Journal of molecular neuroscience : MN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- Vascular Risk Factors and the Risk of Incident Parkinson's Disease Among Stroke Survivors: A Nationwide Population-Based Cohort Study.Journal of clinical medicine · 2026Article
- Small Strokes, Big Impact: Excessive Mortality After Acute Ischemic Stroke in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Moyamoya Disease and the Risk of Parkinson's Disease.Annals of clinical and translational neurology · 2025Article
- Benchmarking the AI-based diagnostic potential of plasma proteomics for neurodegenerative disease in 17,170 people.medRxiv : the preprint server for health sciences · 2025Article
- Prediction of all-cause mortality in Parkinson's disease with explainable artificial intelligence using administrative healthcare data.NPJ Parkinson's disease · 2025Article
- Neurovascular Changes in the Retina of Parkinson's Disease Patients: A Comprehensive Study on Disease Severity, Levodopa Dosage, and Stroke Risk.Noro psikiyatri arsivi · 2025Article
- Mitochondrion-based organellar therapies for central nervous system diseases.Cell communication and signaling : CCS · 2024Review
- Risk of Parkinson disease in stroke patients: A nationwide cohort study in South Korea.European journal of neurology · 2024Article
- Potential Applications of Mitochondrial Therapy with a Focus on Parkinson's Disease and Mitochondrial Transplantation.Advanced pharmaceutical bulletin · 2024Review
- The comorbidity and co-medication profile of patients with progressive supranuclear palsy.Journal of neurology · 2024Article
- Hypoxia Sensing and Responses in Parkinson's Disease.International journal of molecular sciences · 2024Review
- Article
- Impaired neuronal activity as a potential factor contributing to the underdeveloped cerebrovasculature in a young Parkinson's disease mouse model.Scientific reports · 2023Article
- Possible Incidental Parkinson's Disease following Asthma: A Nested Case-Control Study in Korea.Journal of personalized medicine · 2023Article
- Retinal Vessel Density and Retinal Nerve Fiber Layer Thickness: A Prospective Study of One-Year Follow-Up of Patients with Parkinson's Disease.International journal of general medicine · 2023Article
- Economics of Artificial Intelligence in Healthcare: Diagnosis vs. Treatment.Healthcare (Basel, Switzerland) · 2022Article
- Comparison of risk factors for Parkinson's disease, coronary events and ischemic stroke.NPJ Parkinson's disease · 2022Article
- Deep Learning Paradigm for Cardiovascular Disease/Stroke Risk Stratification in Parkinson's Disease Affected by COVID-19: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Cardiovascular Risk Stratification in Diabetic Retinopathy via Atherosclerotic Pathway in COVID-19/Non-COVID-19 Frameworks Using Artificial Intelligence Paradigm: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Cardiovascular/Stroke Risk Stratification in Parkinson's Disease Patients Using Atherosclerosis Pathway and Artificial Intelligence Paradigm: A Systematic Review.Metabolites · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease (PD) and stroke are both associated with aging, but the relationship between these two disorders remains unclear. Recent evidence has shown that they frequently co-occur and are influenced by each another, although some studies have found inconsistent results. We performed this meta-analysis of patients with PD on stroke risk to clarify the relationship between these two disorders on the basis of the studies published from 1975 to July 2019 in the PubMed, EMBASE, and Cochrane Library databases. In total, 13 case-control studies met the inclusion criteria for meta-analysis. The pooled odds ratio (OR) for PD in relation to the stroke risk was 1.72 (95% confidence interval (CI) 1.19-2.49). The OR for the presence of cerebral infarct among PD in the four studies was 1.35 (95% CI 1.04-1.74). Moreover, the OR for the presence of stroke pathology among PD in the four postmortem studies was 1.86 (95% CI 1.17-2.98). In conclusion, our meta-analysis suggests that there is an association between stroke and PD. Sensitivity analysis was used to test the robustness of our results through the sequential removal of each one study at time, in order to investigate if a single study was driving the study results. These results indicate that PD and stroke may have a common pathogenesis and may share preventive treatment measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.