Evidence map›Paper›PMID 32180051›Full record

ArticleNano convergence2020

rGO nanomaterial-mediated cancer targeting and photothermal therapy in a microfluidic co-culture platform.

Seok Gyu Mun, Hyung Woo Choi, Jong Min Lee, Jae Hyun Lim, Jang Ho Ha, Min-Jung Kang, Eun-Joong Kim, Lifeng Kang, Bong Geun Chung

Abstract read
In one paragraph

Article in Nano convergence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
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  6. Review
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  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Cell Analysis on Microfluidics Combined with Mass Spectrometry.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Carbonaceous Nanomaterials for Phototherapy of Cancer.Technology in cancer research & treatment
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seok Gyu MunDepartment of Biomedical Engineering, Sogang University, Seoul, Korea.
Hyung Woo ChoiResearch Center, Sogang University, Seoul, Korea.
Jong Min LeeDepartment of Mechanical Engineering, Sogang University, Seoul, Korea.
Jae Hyun LimDepartment of Biomedical Engineering, Sogang University, Seoul, Korea.
Jang Ho HaDepartment of Mechanical Engineering, Sogang University, Seoul, Korea.
Min-Jung KangResearch Center, Sogang University, Seoul, Korea.
Eun-Joong KimResearch Center, Sogang University, Seoul, Korea.
Lifeng KangSchool of Pharmacy, University of Sydney, Sydney, NSW, Australia.ORCID https://orcid.org/0000-0002-1676-7607
Bong Geun ChungDepartment of Mechanical Engineering, Sogang University, Seoul, Korea. bchung@sogang.ac.kr.ORCID http://orcid.org/0000-0002-6838-3218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We developed the microfluidic co-culture platform to study photothermal therapy applications. We conjugated folic acid (FA) to target breast cancer cells using reduced graphene oxide (rGO)-based functional nanomaterials. To characterize the structure of rGO-based nanomaterials, we analyzed the molecular spectrum using UV-visible and Fourier-transform infrared spectroscopy (FT-IR). We demonstrated the effect of rGO-FA-based nanomaterials on photothermal therapy of breast cancer cells in the microfluidic co-culture platform. From the microfluidic co-culture platform with breast cancer cells and human umbilical vein endothelial cells (HUVECs), we observed that the viability of breast cancer cells treated with rGO-FA-based functional nanomaterials was significantly decreased after near-infrared (NIR) laser irradiation. Therefore, this microfluidic co-culture platform could be a potentially powerful tool for studying cancer cell targeting and photothermal therapy.

Indexed as

Caner targetingMicrofluidic co-culture platformPhotothermal therapyReduced graphene oxiderGO-PEG-FA nanomaterial

Identifiers

PMID32180051
PMCPMC7076105

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.