Evidence map›Paper›PMID 32179932›Full record

Observational studyActa dermato-venereologica2020

Adverse Events Leading to Discontinuation of Phototherapy: An Observational Study.

Isabel Belinchón, María J Sánchez-Pujol, Alejandro Docampo, Laura Cuesta, Luca Schneller-Pavelescu, Jose M Ramos-Rincón

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Acta dermato-venereologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Isabel BelinchónService of Dermatology, General University Hospital of Alicante, C/ Pintor Baeza, 12, ES-03010 Alicante, Spain. belinchon_isa@gva.es.
María J Sánchez-Pujol
Alejandro Docampo
Laura Cuesta
Luca Schneller-Pavelescu
Jose M Ramos-Rincón
Hospital General Universitario de Alicante Doctor Balmis · ESHospital Universitari Sant Joan D'Alacant · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this prospective study in a phototherapy unit was to describe adverse events (AEs) associated with discontinuation of phototherapy in a clinical setting. A total of 872 included patients received 1,256 courses of phototherapy treatment: 76.9% narrow-band UVB (NBUVB); 9.6% systemic psoralen plus UVA (PUVA); 11.4% topical PUVA; and 2.1% UVA. Approximately a fifth of the treatments (n = 240, 19.1%) were associated with AEs, the most frequent of which was erythema (8.8%). Systemic PUVA had the highest rate of AEs (32.5%). Mycosis fungoides was the dermatosis with the highest rate of AE (36.9%). A total of 216 (17.2%) patients stopped treatment: 23.6% because of AEs (4.1% of all treatments). Treatment suspension due to AEs was associated with PUVA, both topical and systemic (p < 0.001), and diagnoses of mycosis fungoides (p <0.001), palmoplantar psoriasis (p = 0.002), hand eczema (p = 0.002) and pityriasis lichenoides (p = 0.01). In conclusion, one in every 5 patients receiving phototherapy had an AE, but few stopped treatment for this reason.

Indexed as

AdultAgedDermatitis, PhototoxicEczemaErythemaFemaleHumansMaleMiddle AgedMycosis FungoidesPainPatient DropoutsPityriasis LichenoidesProspective StudiesPsoriasisPUVA Therapyadverse eventsdiscontinuationnarrow-band UVBphototherapypsoralen plus UVA

Identifiers

PMID32179932
PMCPMC9128872
OpenAlexW3011369533

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.