Evidence map›Paper›PMID 32179926›Full record

ArticleSingapore medical journal2022

Misuse of prescription medicines is as prevalent as the use of recreational drugs and novel psychoactive substances in Singapore: an unrecognised public health issue?

Wui Ling Chan, Paul Ivor Dargan, Colleen Michelle Haynes, Jody Lynn Green, Joshua Curtis Black, Richard Charles Dart, David Michael Wood

Open access · diamondAbstract read
In one paragraph

Article in Singapore medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Alprazolam-related deaths in Scotland, 2004-2020.Journal of psychopharmacology (Oxford, England) · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Wui Ling ChanEmergency Department, Ng Teng Fong General Hospital, Singapore.
Paul Ivor DarganClinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, St Thomas' Hospital; Faculty of Life Sciences and Medicine, King's College London, London, UK.
Colleen Michelle HaynesRocky Mountain Poison and Drug Center (RMPDC), Denver Health, Research Department, Denver, CO, USA.
Jody Lynn GreenInflexxion, Costa Mesa, CA, USA.
Joshua Curtis BlackRocky Mountain Poison and Drug Center (RMPDC), Denver Health, Research Department, Denver, CO, USA.
Richard Charles DartRocky Mountain Poison and Drug Center (RMPDC), Denver Health, Research Department, Denver, CO, USA.
David Michael WoodClinical Toxicology, Guy's and St Thomas' NHS Foundation Trust and King's Health Partners, St Thomas' Hospital; Faculty of Life Sciences and Medicine, King's College London, London, UK.
Denver Health Medical Center · USKing's College London · GBInflexxion (United States) · USNg Teng Fong General Hospital · SGUniversity of Colorado Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Misuse of prescription medicines and the harms associated with such use are growing threats across the world. There is currently, however, limited data on the extent of prescription medicine misuse in Singapore and whether this is a current threat in the country. Methods: An online survey, limited to 1,000 individuals (aged 21 years and over) who were residents in Singapore, was administered through a survey panel company in September 2015. The survey collected information on participant demographics, and their awareness, self-reported lifetime and past-year misuse of commonly available prescription medicines in Singapore as well as the use of a range of recreational drugs and novel psychoactive substances (NPS). Results: Lifetime (6.7%) and past-year (4.8%) misuse of any prescription medicine was comparable to lifetime (6.0%) and past-year (3.0%) use of any recreational drugs/NPS. The top five prescription medicines for lifetime misuse were: diazepam (2.7%); codeine (2.3%); dhasedyl (promethazine, codeine and ephedrine; 1.6%); panadeine (paracetamol and codeine; 1.5%); and methylphenidate (1.2%). The top five drugs for past-year misuse were: diazepam (1.6%); codeine (0.9%); panadeine (0.7%); alprazolam (0.6%); baclofen (0.6%); and gabapentin (0.6%). Conclusion: Misuse of prescription medicine in Singapore was common, with prevalence comparable to the use of recreational drugs/NPS. A common source for misused drugs was physicians. Further studies are required to determine whether this is more widespread in Singapore and establish the different forms of drug diversion, so that appropriate prevention strategies can be implemented.

Indexed as

Illicit DrugsPrescription DrugsSubstance-Related DisordersCodeineDiazepamHumansPrescriptionsPublic HealthSingaporeCodeineDiazepamIllicit DrugsPrescription DrugsBenzodiazepinesdrug abuseGABAergicsopioidsprescription medicine misuse

Identifiers

PMID32179926
PMCPMC9728315
OpenAlexW3011930431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.